Evidence map›Paper›PMID 40810657›Full record

ReviewAngewandte Chemie (International ed. in English)2025

Inter-Nanoparticle FRET for Biosensing: Photophysics Versus Size.

Eduard Madirov, Clara Catros, Niko Hildebrandt, Chloé Grazon

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Inter-Nanoparticle FRET for Biosensing: Photophysics Versus Size.Angewandte Chemie (International ed. in English) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eduard MadirovDepartment of Engineering Physics, McMaster University, Hamilton, ON, M8S 4K1, Canada.ORCID 0000-0001-7092-8523
Clara CatrosUniv. Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, Talence, F-33400, France.ORCID 0009-0001-8032-3744
Niko HildebrandtDepartment of Engineering Physics, McMaster University, Hamilton, ON, M8S 4K1, Canada.ORCID 0000-0001-8767-9623
Chloé GrazonUniv. Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, Talence, F-33400, France.ORCID 0000-0002-4564-8738

Funding

Canada Excellence Research Chairs Program CERC-2022-00072European Research Council 101077364University of Bordeaux, Bordeaux-INP, CNRS, the LIGHTS&T Graduate Program ANR-17-EURE-0027
6 · The paper itself

Abstract

Förster resonance energy transfer (FRET) enables the quantification of nanoscale distances and biomolecular interactions. Luminescent nanoparticles (NPs) are frequently combined with fluorescent dyes or proteins in FRET. However, their use in inter-NP FRET with luminescent NPs as both donor and acceptor remains less common due to the inherent size constraints that can limit FRET efficiencies. This review critically examines the early advances and current state-of-the-art of inter-NP FRET with a focus on the most commonly used NPs, namely quantum dots (QDs), upconversion nanoparticles (UCNPs), and fluorescent organic nanoparticles (FONs). We show how NP sizes, surface shells, and coatings increase FRET-distances; propose how these drawbacks can be overcome or outcompeted by the unique photophysical properties of the NPs; and discuss representative examples of inter-NP FRET for biosensing. High luminescence brightness, outstanding photostability, near-infrared excitation and emission, spectral and temporal multiplexing, and large surfaces for multifunctional bioconjugation are only some of the features that make luminescent NPs very attractive for biosensing, and FRET efficiencies up to 90% have demonstrated their potential for successful translation into bioanalytical applications.

Indexed as

Biosensing TechniquesFluorescence Resonance Energy TransferNanoparticlesFluorescent DyesParticle SizeQuantum DotsFluorescent DyesDyesFluorescencePolymer nanoparticlesQuantum dotsUpconversion nanoparticles

Identifiers

PMID40810657
PMCPMC12455444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.