Evidence map›Paper›PMID 40810456›Full record

ReviewMicrobial biotechnology2025

Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies.

Amechi S Nwankwegu, Sinang Hongsanan, Uzoma P Nwankwegu, Ning Xie

Abstract readReview
In one paragraph

Review in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Virulence · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amechi S NwankweguShenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China.ORCID https://orcid.org/0000-0003-3561-0514
Sinang HongsananShenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China.
Uzoma P NwankweguDepartment of Food Science and Technology, Ebonyi State University, Abakaliki, Nigeria.
Ning XieShenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China.ORCID https://orcid.org/0000-0002-5866-8535

Funding

Guangdong Provincial Key Laboratory for Plant EpigeneticsNational Key R&D Program of China 2021YFA0910800Natural Science Foundation of Guangdong Province 024B1515020034
6 · The paper itself

Abstract

Fruiting body development is a principal mechanism in fungal morphogenesis, which often involves complex interplays of hormonal regulation, gene expression, and metabolic immobilisation influenced by environmental interactions, ultimately leading to the differentiation of multicellular structures. In fungal communities, including ascomycetes and basidiomycetes, fruiting body development ensures protection and facilitates the dispersal of ascospores. Constrained by environmental factors that vary across morphogenetic stages, a thorough synthesis of the critical ecological optima, which primarily regulate the multi-omics footprint encompassing diverse molecular perspectives characterising fruiting body formations, is key. It underscores that exceeding the critical environmental ranges triggers dynamic shifts that adversely impact the fruiting body's eco-resilience; however, operating below these optima is safer, as most fruiting body physiological activities are generally able to maintain normal functioning and stability, making the present study relevant to decision-makers for optimal fruiting body commercialisation. It elucidates the recent advances in fruiting body biotechnologies, traversing agricultural/food, optimised cultivation strategies, environmental and health, bioactive compounds extractions, genetic engineering, and synthetic biology, promoting scalable bioproduction. Nonetheless, it proposes further studies emphasising omics-driven strain-substrate improvements/genomic modifications, incorporating CRISPR advances, to boost precision cultivation and enhance robust strain design. The study offers promising insights into complementing existing knowledge on fungal fruiting bodies and addresses challenges related to environmental complexity and uncertainties, aiming to drive sustainable industrial biotechnology.

Indexed as

AscomycotaBasidiomycotaBiotechnologyFruiting Bodies, Fungalcritical environmental optimafruiting body biotechnology: epigenetic regulationfungal fruiting body developmentmulti‐omics

Identifiers

PMID40810456
PMCPMC12351640

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.