ArticleJournal of veterinary internal medicine
Microbial Gene Profiling and Targeted Metabolomics in Fecal Samples of Dogs With Chronic Enteropathy With or Without Increased Dysbiosis Index.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Quantitative assessment of specific bacterial taxa of the intestinal microbiota of healthy and diarrheic horses.Journal of veterinary internal medicine · 2026Article
- Faecal Microbiota Transplantation Reduces Lesion Severity and Medication Use in Canine Atopic Dermatitis: A Randomised, Placebo-Controlled, Double-Blinded Clinical Trial.Veterinary dermatology · 2026Article
- Fasting Serum Bile Acid Profiles in Dogs with Food-Responsive and Immunosuppressant-Responsive Chronic Inflammatory Enteropathy: An Exploratory LC-MS/MS Study.Animals : an open access journal from MDPI · 2026Article
- Effect of low dose azithromycin on the fecal microbiome and fecal bile acids in healthy dogs.Journal of veterinary internal medicine · 2026Article
- Coprophagy in Healthy Dogs Does Not Alter Fecal Core Microbiota or Increase Carriage of Enteropathogens.Animals : an open access journal from MDPI · 2026Article
- PasteurizedMicrobiology spectrum · 2026Article
- The Collaborative Collapse: Bile Acid Dysmetabolism as a Central Pathogenic Driver in Canine and Feline Multi-Systemic Disorders-From Mechanisms to Precision Therapeutics.Veterinary sciences · 2026Review
- Microbial Gene Profiling and Targeted Metabolomics in Fecal Samples of Dogs With Chronic Enteropathy With or Without Increased Dysbiosis Index.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundIn previous studies, only a subset of dogs with chronic enteropathy (CE) had an increased dysbiosis index (DI) or altered fecal metabolites or both, suggesting differences in underlying intestinal pathophysiology between these subsets.
objectivesTo compare microbial functional genes and fecal metabolites between healthy dogs with DI < 0 (HC) and dogs with CE and DI > 0 (increased DI-CE) or DI < 0 (normal DI-CE). ANIMALS: Retrospective cross-sectional study including 78 HC and 138 CE dogs.
methodsFecal microbiome was assessed by DNA shotgun sequencing. Dysbiosis index was quantified by qPCR. Targeted fecal metabolites, long-chain fatty acids, sterols, bile acids (BAs), and carbohydrates were measured using gas chromatography-mass spectrometry (GC-MS).
resultsIn permutational analysis of variance (PERMANOVA), functional gene profiles showed larger shifts in increased DI-CE (median R
conclusionsResults indicate differences in fecal microbial gene profiles and metabolome in increased DI-CE versus normal DI-CE and HC, suggesting dogs with an increased DI have more severe intestinal changes in metabolic functions.
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