Evidence map›Paper›PMID 40810172›Full record

ArticleACS pharmacology & translational science2025

Photodynamic Therapy Using a Heavy-Atom-Free G‑Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo.

Eva Rodriguez-Marquez, Hanna Nord, Darío Puchán Sánchez, Ahmad Kassem, José María Andrés Castán, Marco Deiana, Clement Cabanetos, Nasim Sabouri, Jonas von Hofsten

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Light-Activated Molecules Targeting G-Quadruplex Nucleic Acids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eva Rodriguez-MarquezDepartment of Medical and Translational Biology, Umeå University, 90187 Umeå, Sweden.ORCID https://orcid.org/0000-0002-5631-2332
Hanna NordDepartment of Medical and Translational Biology, Umeå University, 90187 Umeå, Sweden.
Darío Puchán SánchezUniversity Angers, CNRS, MOLTECH-ANJOU, SFR MATRIX, F-49000 Angers, France.ORCID https://orcid.org/0009-0006-7176-080X
Ahmad KassemUniversity Angers, CNRS, MOLTECH-ANJOU, SFR MATRIX, F-49000 Angers, France.
José María Andrés CastánUniversity Angers, CNRS, MOLTECH-ANJOU, SFR MATRIX, F-49000 Angers, France.
Marco DeianaInstitute of Advanced Materials, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.ORCID https://orcid.org/0000-0002-7815-4494
Clement CabanetosUniversity Angers, CNRS, MOLTECH-ANJOU, SFR MATRIX, F-49000 Angers, France.ORCID https://orcid.org/0000-0003-3781-887X
Nasim SabouriDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187 Umeå, Sweden.ORCID https://orcid.org/0000-0002-4541-7702
Jonas von HofstenDepartment of Medical and Translational Biology, Umeå University, 90187 Umeå, Sweden.ORCID https://orcid.org/0000-0003-3730-1790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdomyosarcoma is a highly aggressive soft tissue cancer that predominantly affects children and adolescents. Current treatment outcomes are poor, highlighting the urgent need for potent therapeutic alternatives. Preclinical research on photodynamic therapy (PDT) continues to gain attention as a promising and minimally invasive treatment strategy. Recently, PDT using the heavy-atom-free photosensitizer dibenzothioxanthene imide (

Indexed as

cancerG-quadruplexphotodynamic therapyphotosensitizerrhabdomyosarcomazebrafish

Identifiers

PMID40810172
PMCPMC12340618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.