Evidence map›Paper›PMID 40809987›Full record

ArticleBiomedical optics express2025

Axicons for improved resolution and depth of focus in adaptive optics scanning light ophthalmoscopy.

Ruth E Woehlke, Robert F Cooper

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ruth E WoehlkeJoint Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Robert F CooperJoint Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0002-0796-1387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive optics scanning light ophthalmoscopes are instrumental for studying the eye, yet they use truncated Gaussian illumination and are limited by diffraction, restricting resolution and depth of focus (DOF). Non-diffractive Bessel beams have emerged as an alternative. Here, we use two axicons configured as: (1) an extended DOF beam for resolving multiple retinal layers; and (2) an annular beam for increasing lateral resolution. We compare both approaches to truncated Gaussian illumination using a variety of metrics. Using Configuration 1, we successfully observed multiple retinal layers simultaneously. Using Configuration 2, we observed enhanced lateral resolution but decreased signal-to-noise ratio.

Identifiers

PMID40809987
PMCPMC12339292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.