Evidence map›Paper›PMID 40809985›Full record

ArticleBiomedical optics express2025

Wide-field quantitative micro-elastography of freshly excised human prostate.

Szymon Tamborski, Marta K Skrok, Matt S Hepburn, Mateusz Maniewski, Marek Zdrenka, Adam Kowalewski, Łukasz Szylberg, Brendan F Kennedy

Erratum issuedAbstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Szymon TamborskiInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, 5 Grudziądzka St., 87-100 Toruń, Poland.ORCID https://orcid.org/0000-0002-3636-5824
Marta K SkrokInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, 5 Grudziądzka St., 87-100 Toruń, Poland.ORCID https://orcid.org/0000-0002-2768-9595
Matt S HepburnInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, 5 Grudziądzka St., 87-100 Toruń, Poland.ORCID https://orcid.org/0000-0001-5953-4478
Mateusz ManiewskiDepartment of Obstetrics, Gynaecology and Oncology, Chair of Pathomorphology and Clinical Placentology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 75 Ujejskiego St., Bydgoszcz 85-168, Poland.
Marek ZdrenkaDepartment of Tumor Pathology and Pathomorphology, Oncology Centre Prof. Franciszek Łukaszczyk Memorial Hospital, 2 Romanowskiej St., Bydgoszcz 85-796, Poland.
Adam KowalewskiDepartment of Tumor Pathology and Pathomorphology, Oncology Centre Prof. Franciszek Łukaszczyk Memorial Hospital, 2 Romanowskiej St., Bydgoszcz 85-796, Poland.
Łukasz SzylbergDepartment of Obstetrics, Gynaecology and Oncology, Chair of Pathomorphology and Clinical Placentology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 75 Ujejskiego St., Bydgoszcz 85-168, Poland.
Brendan F KennedyInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, 5 Grudziądzka St., 87-100 Toruń, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is a significant global health issue. To advance diagnostic and treatment procedures, such as image-guided needle biopsy, optical imaging methods offering high spatial resolution have been proposed. Optical coherence tomography (OCT) allows for detailed visualization of prostate microarchitecture in three dimensions; however, it does not reliably differentiate tumors from surrounding healthy tissue. In this study, we use wide-field quantitative micro-elastography (QME) to image the micro-scale mechanical properties of freshly excised human prostate to provide additional contrast of tumor, which is known to exhibit increased stiffness. In our approach, we generate volumetric OCT, strain, and elasticity images over a field-of-view (

Identifiers

PMID40809985
PMCPMC12339301

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.