Evidence map›Paper›PMID 40809946›Full record

ReviewVeterinarni medicina2025

Animal models of autism spectrum disorder: Insights into genetic, structural and environmental models.

Dariya Chivchibashi-Pavlova, Kameliya Bratoeva

Abstract readReview
In one paragraph

Review in Veterinarni medicina, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dariya Chivchibashi-PavlovaDepartment of Physiology and Pathophysiology, Faculty of Medicine, Medical University - Varna, Varna, Bulgaria.ORCID 0000-0002-6520-7569
Kameliya BratoevaDepartment of Physiology and Pathophysiology, Faculty of Medicine, Medical University - Varna, Varna, Bulgaria.ORCID 0000-0002-6235-3384

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a group of human neurodevelopmental disorders with significant global prevalence. Deficits in social communication and interaction and repetitive, stereotyped patterns of behaviour characterise ASD. The aetiology of ASD is unclear, but several genetic and environmental risk factors, either alone or in combination, are implicated in its development. To date, the underlying pathogenic mechanisms of ASD remain incompletely understood due to its heterogeneity. To better understand the pathogenesis of ASD, various animal models have been developed. The use of animals in ASD research allows the exploration of the biological substrates of social behaviour, cognition, and reward sensitivity, which are key components of ASD symptoms. This review outlines the commonly employed animal models in ASD research and explores their applications and the associated challenges.

Indexed as

animal experimental modelsnovel experimental modelsprimate modelsrodent modelszebrafish models

Identifiers

PMID40809946
PMCPMC12342127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.