Evidence map›Paper›PMID 40809918›Full record

ArticleToxicology research2025

Curcumin nanoparticles ameliorates cardiac toxicity through modulation of oxidative stress, apoptosis, inflammation, and DNA damage in rat.

Ehab Tousson, Doha Mohammad Beltagy, Nagat Fawzy Nawar, Mona A Dora, Hamed Muhammad Abdel Bari, Ibrahim E T El-Sayed

Abstract read
In one paragraph

Article in Toxicology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ehab ToussonZoology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.ORCID https://orcid.org/0000-0001-9722-3603
Doha Mohammad BeltagyDepartment of Chemistry, Faculty of Science, Damanhour University, 22511, Egypt.
Nagat Fawzy NawarDepartment of Chemistry, Faculty of Science, Tanta University, 31527, Egypt.ORCID https://orcid.org/0009-0002-2656-8668
Mona A DoraDepartment of Chemistry, Faculty of Science, Menoufia University, 32511, Egypt.
Hamed Muhammad Abdel BariDepartment of Chemistry, Faculty of Science, Menoufia University, 32511, Egypt.
Ibrahim E T El-SayedDepartment of Chemistry, Faculty of Science, Menoufia University, 32511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have highlighted the toxicological impact of nanoparticles, including their role in malignancies and various organ system dysfunctions, however, the effects of nanoparticles on the cardiovascular system remain underexplored. Their fore; this study designed to investigate the therapeutic effect of Curcumin (Cur) and/or Curcumin nanoparticles (CurNPs) against Copper oxide nanoparticles (CuONPs) induced toxicity, DNA damage, oxidative stress, apoptosis and inflammation in rat cardiac tissues. A total of 60 adult male rats were assigned randomly to 6 groups [1

Indexed as

copper oxide nanoparticlescurcumin nanoparticlesheartoxidative stressPCNATNFα

Identifiers

PMID40809918
PMCPMC12342465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.