Evidence map›Paper›PMID 40809792›Full record

ArticleGlobal mental health (Cambridge, England)2025

The moderating and mediating role of resilience in the relationship between adverse childhood experiences and depression, PTSD, and suicidality in Kenyan youth.

Victoria Mutiso, David Ndetei, Eric Jeremiah, Pascalyne Nyamai, Samuel Walusaka, Veronica Onyango, Christine Musyimi, Kamaldeep Bhui, Daniel Mamah

Abstract read
In one paragraph

Article in Global mental health (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Victoria MutisoAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
David NdeteiAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.ORCID https://orcid.org/0000-0001-6891-4990
Eric JeremiahAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
Pascalyne NyamaiAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
Samuel WalusakaAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
Veronica OnyangoAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
Christine MusyimiAfrica Institute of Mental and Brain Health (formerly Africa Mental Health Research and Training Foundation), Nairobi, Kenya.
Kamaldeep BhuiDepartment of Psychiatry, Nuffield Department of Primary Care Health Sciences, Wadham College, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-9205-2144
Daniel MamahDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse childhood experiences (ACEs) are widely associated with mental health disorders, such as depression, post-traumatic stress disorder (PTSD), and suicidality. Resilience plays a role in mediation and moderation of these associations, yet there is limited data from Kenya on this. This cross-sectional study examined the role of resilience in the relationship between ACEs and mental health outcomes among 1,972 participants aged 14-25 years in the Nairobi Metropolitan area. Participants completed the Trauma and Distress Scale (ACEs), Patient Health Questionnaire-9 (depression), Columbia-Suicide Severity Rating Scale (suicidality), Harvard Trauma Questionnaire (PTSD), and Adult Resilience Measure-Revised (resilience). Analyses of moderation and mediation using Hayes Process Macro indicated that resilience moderated the association between ACEs with PTSD and depression, with minimal effect on suicidality. It also moderated specific associations, including emotional/physical neglect on ideation, physical abuse on lifetime behavior (

Indexed as

ACEsdepressionPTSDresiliencesuicidality

Identifiers

PMID40809792
PMCPMC12345062

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.