Evidence map›Paper›PMID 40809790›Full record

ArticleSurgery open science2025

S-EMR: A first experience with stalked endoscopic mucosal resection in thick and high-risk pedunculated polyps.

Mojgan Forootan, Alessandro Repici, Mohsen Rajabnia, Ali Jahanian, Mahsa Mohammadi, Mohammad Reza Zali, Hamidreza Bolhasani

Abstract read
In one paragraph

Article in Surgery open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mojgan ForootanGastroenterology and Liver Disease Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alessandro RepiciHumanitas University & Humanitas Research Hospital, Milano, Italy.
Mohsen RajabniaNon-Communicable Disease Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Ali JahanianGastroenterology and Liver Disease Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahsa MohammadiNon-Communicable Disease Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Mohammad Reza ZaliGastroenterology and Liver Disease Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hamidreza BolhasaniIslamic Azad University Science and Research Branch Tehran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-polypectomy bleeding (PPB) is a relatively common event after polypectomy of large polyps using conventional methods, and the likelihood of malignant tissue remaining remains. The aim of this study was to investigate the efficacy of stalked endoscopic mucosal resection (S-EMR) as a potential solution to PPB in large pedunculated and semi-pedunculated colonic polyps and to reduce the need for repeat endoscopic intervention and surgery for malignant polyps. Methods: This prospective, single-arm, open-label study was conducted on patients in whom screening colonoscopy was indicated. All patients who were found to have pedunculated and semi-pedunculated polyps (Paris class Ip and Ips) with a thick stalk (>10 mm), a polyp head ≥20 mm in size, giant polyps leading to bowel obstruction, or large polyps with JNET type 2B or type3 were included in this study. These polyps were treated with S-EMR method, instead of conventional current methods like utilizing endoloops and clips in the base of stalks: Lift-and-cut technique after formation of adequate submucosal cushion in the base of the pedicle and subsequent prophylactic cauterization of the underlying blood vessels. After the procedure, patients were monitored for vital signs and symptoms of immediate complications for 6 h post-procedure and up to 48 h after discharge. Results: A total of 48 patients were included in the study. The mean age of the patients was 62.24 years and 41.6 % of them were male. Ten patients had pedunculated and 38 patients had semi-pedunculated polyps. The most common localization of polyps was sigmoid (45.8 %). After S-EMR, no patient had early or late PPB. Four large semi-pedunculated polyps were diagnosed as adenocarcinoma. All had clear margins and no signs of neoplastic submucosal invasion on histologic evaluation. Conclusion: S-EMR is a safe method for removing thick-stalked, giant, high-risk, and malignant, pedunculated, and semi-pedunculated polyps. It may reduce the risk of PPB and assist in achieving clear margins in malignant polyps.

Indexed as

Colorectal cancerEndoscopic mucosal resection (EMR)Pedunculated polypsPolypectomySemi-pedunculated polyps

Identifiers

PMID40809790
PMCPMC12346001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.