Evidence map›Paper›PMID 40809653›Full record

ArticleCureus2025

Congenital Cytomegalovirus Pneumonitis Mimicking Childhood Interstitial Lung Disease: A Case Report and Review of Diagnostic Challenges.

Khalfan Al Abdali, Talal Al Wardi, Ruba Elfatih, Yarab Al Bulushi, Majid Al Jabri

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khalfan Al AbdaliDepartment of Pediatrics, Nizwa Hospital, Ministry of Health, Nizwa, OMN.
Talal Al WardiDepartment of Pediatrics, Nizwa Hospital, Ministry of Health, Nizwa, OMN.
Ruba ElfatihDepartment of Pediatrics, Nizwa Hospital, Ministry of Health, Nizwa, OMN.
Yarab Al BulushiDepartment of Radiology, College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, OMN.
Majid Al JabriDepartment of Child Health, College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, OMN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a full-term neonate with congenital cytomegalovirus (CMV) infection manifesting as severe pneumonitis. The patient exhibited intrauterine growth restriction (IUGR), early onset of respiratory distress, and persistent oxygen dependency. High viral load in urine and plasma supported the diagnosis, confirmed within the first three weeks of life. Despite treatment with oral valganciclovir for six months, persistent tachypnea, failure to thrive, and radiological findings prompted a broader differential diagnosis, including childhood interstitial lung disease (chILD). Bronchoscopy and whole-exome sequencing (WES) were performed. This case underscores the need for multidisciplinary evaluation in neonates with unexplained or protracted respiratory illness and highlights the potential overlap between congenital CMV pneumonitis and genetic interstitial lung disease (ILD).

Indexed as

childhood interstitial lung diseasecongenital cytomegalovirus infectionfiberoptic flexible bronchoscopyneonatal respiratory distresswhole-exome sequencing

Identifiers

PMID40809653
PMCPMC12344389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.