Evidence map›Paper›PMID 40809630›Full record

ArticleCureus2025

Adult-Onset Still's Disease in a 49-Year-Old Female in the UAE: A Case Report and Literature Review.

Nagwa M Ali, Mohammed O Ibrahim, Osama M Mohamed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nagwa M AliRheumatology, Mediclinic Airport Road Hospital, Abu Dhabi, ARE.
Mohammed O IbrahimClinical Sciences, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, ARE.
Osama M MohamedFamily Medicine, SEHA Clinics, Abu Dhabi Health Services Company (SEHA), Abu Dhabi, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult-onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by high spiking fevers, salmon-colored rash, arthritis, and hyperferritinemia. It often mimics infections or autoimmune conditions, leading to diagnostic delays. We report a case of a 49-year-old female who presented with fever, fatigue, arthralgia, evanescent rash, and elevated inflammatory markers. Extensive infectious and autoimmune workups were negative. Her serum ferritin exceeded 16,000 ng/mL. She fulfilled the Yamaguchi criteria for AOSD, and treatment with corticosteroids followed by tocilizumab resulted in marked clinical improvement. This is, to our knowledge, the first documented case of AOSD from the UAE. It underscores the importance of ferritin in diagnosis and disease monitoring and highlights the efficacy of interleukin (IL)-6 inhibition in management.

Indexed as

adult-onset still’s diseasebiological therapyhyperferritinemiasalmon-pink rashyamaguchi criteria

Identifiers

PMID40809630
PMCPMC12343192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.