ArticleCureus2025
Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Microbiota and head and neck cancers: Mechanistic insights and translational potential.Virulence · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective This study aimed to assess whether a statistically significant correlation exists between socioeconomic status, measured by the Index of Multiple Deprivation (IMD), and the incidence of head and neck cancer (HNC) in Greater Manchester and East Cheshire. Understanding this relationship can help inform targeted public health interventions and reduce healthcare disparities. Methods Using Multidisciplinary Team (MDT) lists, 236 HNC patients from Manchester University NHS Foundation Trust were identified. Patient demographics and residential postcodes were extracted from the HIVE electronic patient record system. Postcodes were then mapped to IMD deciles using the UK Government's official postcode-to-IMD lookup tool. This allowed for the categorisation of patients by area-level socioeconomic deprivation. Results The analysis revealed a negative correlation (ρ = -0.21) between socioeconomic status, as indicated by IMD decile, and the incidence of HNC cases. Statistical analysis showed that this correlation was not statistically significant at the α = 0.05 level. Conclusion While this study did not identify a statistically significant correlation between socioeconomic deprivation and HNC incidence, a weak negative trend was observed. These exploratory findings suggest potential geographic and socioeconomic patterns that warrant further investigation. Understanding these trends may support more targeted public health strategies - especially in regions with a higher disease burden - and contribute to efforts aimed at earlier diagnosis and improved health outcomes.
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Registered trials
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