Evidence map›Paper›PMID 40809499›Full record

ArticleFrontiers in systems biology2023

Synergistic effects of complex drug combinations in colorectal cancer cells predicted by logical modelling.

Evelina Folkesson, B Cristoffer Sakshaug, Andrea D Hoel, Geir Klinkenberg, Åsmund Flobak

Abstract read
In one paragraph

Article in Frontiers in systems biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Evelina FolkessonDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
B Cristoffer SakshaugDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Andrea D HoelDepartment of Biotechnology, SINTEF Materials and Chemistry, Trondheim, Norway.
Geir KlinkenbergDepartment of Biotechnology, SINTEF Materials and Chemistry, Trondheim, Norway.
Åsmund FlobakDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug combinations have been proposed to combat drug resistance in cancer, but due to the large number of possible drug targets,

Indexed as

colorectal cancerdrug combinationslogical modellingpredictionsynergy

Identifiers

PMID40809499
PMCPMC12342003

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.