Evidence map›Paper›PMID 40809469›Full record

ArticleJAMIA open2025

EchoLLM: extracting echocardiogram entities with light-weight, open-source large language models.

Jonathan Chi, Yazan Rouphail, Ethan Hillis, Ningning Ma, An Nguyen, Jane Wang, Mackenzie Hofford, Aditi Gupta, Patrick G Lyons, Adam Wilcox and 5 more

Abstract read
In one paragraph

Article in JAMIA open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jonathan ChiGoergen Institute for Data Science and Artificial Intelligence, University of Rochester, Rochester, NY 14627, United States.ORCID https://orcid.org/0009-0004-4751-3660
Yazan RouphailDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0002-1859-3225
Ethan HillisDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.
Ningning MaDivision of Hospital Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.
An NguyenDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.
Jane WangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.
Mackenzie HoffordDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0001-8256-2127
Aditi GuptaDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.
Patrick G LyonsDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, United States.ORCID https://orcid.org/0000-0002-1557-2787
Adam WilcoxDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.
Albert M LaiDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0002-9241-2656
Philip R O PayneDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0002-9532-2998
Marin H KollefDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.
Caitlin DreisbachGoergen Institute for Data Science and Artificial Intelligence, University of Rochester, Rochester, NY 14627, United States.ORCID https://orcid.org/0000-0003-3964-3161
Andrew P MichelsonDepartment of Medicine, Institute for Informatics, Data Science and Biostatistics, Washington University in St. Louis, St. Louis, MO 63110, United States.

Funding

PRINCIPLES IN PULMONARY RESEARCHT32HL007317 · NHLBI · WASHINGTON UNIVERSITY · PI Steven Brody, Michael J Holtzman · 1985 to 2026
$16.1M
NHLBI NIH HHS T32 HL007317
6 · The paper itself

Abstract

Objectives: Large language models (LLMs) have demonstrated high levels of performance in clinical information extraction compared to rule-based systems and traditional machine-learning approaches, offering scalability, contextualization, and easier deployment. However, most studies rely on proprietary models with privacy concerns and high costs, limiting accessibility. We aim to evaluate 14 publicly available open-source LLMs for extracting clinically relevant findings from free-text echocardiogram reports and examine the feasibility of their implementation in information extraction workflows. Materials and Methods: We used 14 open-source LLM models to extract clinically relevant entities from echocardiogram reports ( Results: In aggregate, Gemma2:9b-instruct had the highest precision, recall, and F1 scores at 0.973 (0.962-0.983), 0.959 (0.947-0.973), and 0.965 (0.951-0.975), respectively. In comparison, Phi3:3.8b-mini-instruct had the lowest precision score at 0.831 (0.804-0.856), while Gemma:7b-instruct had the lowest recall and F1 scores at 0.382 (0.356-0.408) and 0.392 (0.356-0.428), respectively. Discussion and Conclusion: Using LLMs for entity extraction for echocardiogram reports has the potential to support both clinical research and health-care delivery. Our work demonstrates the feasibility of using open-source models for more efficient computation and extraction.

Indexed as

clinical and research data collectionclinical decision supportelectronic health recordslarge language modelsnatural language processing

Identifiers

PMID40809469
PMCPMC12349756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.