ArticleFrontiers in medicine2025
Exploring the differences in mortality and its associated factors among young-old and old-old COVID-19 patients.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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6 authors.
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Abstract
Background: This study aims to compare the differences in mortality and related factors between old-old and young-old COVID-19 patients and find unique factors related to survival in old-old patients. Study design: Single-center retrospective cohort study following STROBE guidelines. Methods: We included 302 elderly (≥65 years old) COVID-19 patients admitted to Shijiazhuang People's Hospital from December 1, 2022 to March 31, 2023. Among them, 142 were assigned to the young-old group (65-74 years old) and 160 in the old-old group (≥75 years old). Demographic, clinical and laboratory data were extracted, and descriptive statistical analysis, comparison of differences between groups, Cox proportional hazards regression analysis, and subgroup analysis were adopted. Results: Compared with the young-old group, the mortality of old-old patients was higher (31.3% vs. 12.7%, Conclusion: This study found for the first time that dyspnea symptoms, acute heart injury, diabetes, and glucocorticoid therapy are unique risk factors related to survival in old-old patients with COVID-19. These factors need more attention when treating old-old patients to prevent poor prognosis.
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