Evidence map›Paper›PMID 40809392›Full record

ArticleOpen forum infectious diseases2025

Epidemiological Analysis of Tuberculosis Transmission, Risk Factors, and Subclinical Tuberculosis Management in a High School Outbreak, South Korea.

Yun Choi, Su Jin Park, Hee Seon An, Hyun Mi Kim, Ji Yeon Yoo, Seong Wook Pyo, Jin Su Song, Seung Eun Lee

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun ChoiDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-5883-9472
Su Jin ParkDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0006-7500-6185
Hee Seon AnDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0000-8916-6231
Hyun Mi KimDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0007-6185-1887
Ji Yeon YooDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-3661-8809
Seong Wook PyoDivision of Bacterial Disease, Department of Laboratory Diagnosis and Analysis, Korea Disease Control and Prevention Agency, Chengju, Republic of Korea.ORCID https://orcid.org/0000-0001-8775-3571
Jin Su SongSeoul National University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-0050-8018
Seung Eun LeeDivision of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0004-8650-5591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tuberculosis (TB) remains a significant public health concern, particularly in congregate settings such as schools, where adolescents are at increased risk transmission. This study aimed to investigate the epidemiological characteristics, transmission dynamics, and control strategies during a TB outbreak in a South Korean high school. Methods: A retrospective epidemiological investigation was conducted using data from the Korea Tuberculosis Network and official outbreak reports. A total of 935 individuals-including students, staff, and household contacts-underwent screening through chest X-rays, interferon-gamma release assays (IGRAs), and chest computed tomography (CT). Genotyping of Results: Among 935 contacts, 133 (14.2%) tested positive for TB infection. In total, 30 cases of TB disease and 66 cases of latent TB infection were identified among 762 student contacts. Prolonged exposure exceeding 10 hours per week was associated with a significantly increased risk of TB infection (adjusted odds ratio = 5.91, 95% confidence interval: 3.06-11.40, Conclusions: This outbreak highlights the importance of rapid TB diagnosis, targeted screening for high-risk groups, and advanced diagnostic tools such as IGRA and CT in identifying subclinical cases. Strengthened contact investigations and expanded preventive strategies, including household contacts, are essential for effective outbreak control.

Indexed as

epidemiologic investigationlatent tuberculosis infection (LTBI)school-based transmissionsubclinical tuberculosistuberculosis outbreak

Identifiers

PMID40809392
PMCPMC12345623

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.