ArticleJournal of thoracic disease2025
Postoperative outcomes in pulmonary nodule patients: a comparative analysis of aggressive
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There is no standard treatment for pulmonary nodules (PNs) detected through computed tomography (CT) scan. Both aggressive intervention and conservative monitoring present their respective advantages and disadvantages. To investigate the impact of aggressive management and conservative management on lung cancer diagnosis rates, postoperative symptoms, and patients' postoperative psychological status after surgeries, the survey was conducted. Methods: A total of 604 patients were enrolled and divided into two groups: the aggressive management group (n=441), with surgery within 365 days after initial CT scan of the nodule, and the conservative management group (n=163), with surgery after a follow-up period exceeding 365 days. Clinical data, imaging characteristics after diagnosis of PNs and pathological diagnosis after the surgery were collected. Other information, including postoperative symptoms, survival, and assessments of anxiety, depression, and sleep disorders were followed up by phone. Changes in nodule size and density were assessed and categorized as unchanged, increased, or decreased by comparing initial and preoperative CT scans. We employed propensity score-matched analysis and multivariable logistic regression to examine the associations between treatment groups and 3-month symptoms, as well as 3-year quality-of-life indicators. Results: After propensity score matching, a total of 396 patients were included in the analysis, including 132 in the conservative group and 264 in the radical group. The aggressive management group had 215 cases (81.4%) of lung cancer diagnosis, having a lower incidence rate than the conservative management group with 118 cases (89.4%). The aggressive management group presented with a lower frequency of invasive adenocarcinoma (IA) type (9.5% Conclusions: Aggressive management effectively reduces IA-type incidence and boosts early detection of stage IA lung cancer, yet it may increase postoperative symptoms like cough, pain, and dyspnea, risking overtreatment. Nonetheless, it may positively alleviate the postoperative anxiety and depression in patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.