Evidence map›Paper›PMID 40809239›Full record

ReviewJournal of thoracic disease2025

Tailored single-lung ventilation approaches and postoperative pulmonary outcomes in thoracic surgery.

Yun Sha, Rui Xu, Shihao Shao, Jinyuan Yang, Beining Tang, Qingna Liang, Zhonghui Wang

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yun ShaDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.
Rui XuDepartment of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Shihao ShaoDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.
Jinyuan YangDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.
Beining TangDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.
Qingna LiangDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.
Zhonghui WangDepartment of Anesthesiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional lung-protective ventilation [low tidal volume (VT) with fixed positive end-expiratory pressure (PEEP)] reduces intraoperative lung injury but exhibits limited efficacy in preventing postoperative pulmonary complications (PPCs) following thoracic surgery requiring one-lung ventilation (OLV). This review systematically examines the multifactorial mechanisms of OLV-associated lung injury, encompassing hypoxemia [device malposition, atelectasis, ventilation/perfusion (V/Q) mismatch, impaired hypoxic pulmonary vasoconstriction (HPV)], oxidative stress, ischemia-reperfusion injury (IRI) (glycocalyx degradation, mechanical stress, inflammation), and ventilator-induced trauma (volutrauma, biotrauma). To address these limitations, we propose an open-lung protective ventilation strategy integrating alveolar recruitment maneuvers (RMs) with individualized PEEP (iPEEP) titration based on optimal respiratory compliance. Furthermore, we innovatively introduce oxygen reserve index (ORI)-guided titration of fraction of inspired oxygen (FiO

Indexed as

lung injurymechanical ventilationOne-lung ventilation (OLV)postoperative pulmonary complications (PPCs)tailored lung protective ventilation strategies

Identifiers

PMID40809239
PMCPMC12340303

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.