ArticleJournal of thoracic disease2025
Effect of respiratory filter resistance on respiratory mechanics and human-machine synchrony during invasive jet atomization: a prospective self-controlled study.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To reduce the contamination of the breathing circuit, respiratory filters are used in patients receiving mechanical ventilation. However, their use increases the resistance and dead space volume of the breathing circuit, which potentially leads to asynchrony events, especially when patients are receiving jet nebulization. However, the impact of respiratory filter resistance on respiratory mechanics and human-machine synchronization during invasive ventilation with jet nebulization is not clear. Therefore, this study aims to investigate the question above and optimize the strategy of clinical filter using which may advance implementing lung-protective ventilation. Methods: The study carried out a self-controlled study and enrolled 12 patients receiving mechanical ventilation and monitored changes in respiratory mechanics and human-machine synchronization indicators under varying numbers of respiratory filters during jet nebulization. Results: The study found that jet nebulization, the use of respiratory filters and increasing filter resistance exacerbated abnormal triggering and asynchrony index [abnormal triggering: G1 Conclusions: Increasing respiratory filter resistance during jet nebulization may exacerbate human-machine asynchronicity. Therefore, the use of filters during nebulization in invasive ventilation patients should be carefully considered, and filters should be replaced promptly after nebulization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.