Evidence map›Paper›PMID 40809206›Full record

ReviewJournal of thoracic disease2025

Advances in vagus nerve management strategies in thoracoscopic lung resections: a narrative review.

Hongjin Ni, Yongjie Li, Gang Shen, Lina Yu

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Role of the Nervous System in Lung Disease.Current neurology and neuroscience reports · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongjin NiDepartment of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0009-0001-0650-9671
Yongjie LiDepartment of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Gang ShenDepartment of Thoracic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Lina YuDepartment of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0003-1342-2969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: The vagus nerve (VN) is a critical component of the parasympathetic nervous system, playing a pivotal role in respiratory, cardiovascular, and digestive functions. Its management during thoracoscopic lung resections is essential to minimize postoperative complications such as cough and arrhythmias. This review aims to explore advancements in VN management strategies-including preservation, neuromonitoring, and nerve block-and their impact on surgical outcomes and long-term recovery. Methods: A literature search was conducted in PubMed, China National Knowledge Infrastructure (CNKI), and Google Scholar databases for studies published between January 2010 and March 2025. The search used Medical Subject Headings (MeSH) terms and free-text keywords such as "vagus nerve", "thoracoscopic lung resections", "intraoperative monitoring", and "postoperative complications", combined with Boolean operators. Inclusion criteria focused on original full-text articles in English or Chinese evaluating VN management in thoracoscopic lung surgery. Exclusion criteria included animal studies, case reports, and non-peer-reviewed publications. Key Content and Findings: The preservation of the pulmonary branch of the VN has been shown to significantly reduce postoperative cough and facilitate recovery. However, some studies suggest that a highly selective severance strategy might be more effective. The development of continuous intraoperative nerve monitoring has improved procedure safety and reduced complications. VN block offers advantages in non-intubated thoracoscopic surgery by suppressing cough reflexes and enhancing patient comfort. Conclusions: While the preservation of the VN branches appears beneficial, the optimal strategy for VN management during thoracoscopic lung resection remains a subject of ongoing research. Future studies should aim to clarify the mechanisms by which VN management affects postoperative outcomes and establish evidence-based guidelines for clinical practice, potentially improving surgical safety and patient recovery.

Indexed as

intraoperative neuromonitoring (IONM)pulmonary branch preservationthoracoscopic lung resectionsvagus nerve block (VNB)Vagus nerve management (VN management)

Identifiers

PMID40809206
PMCPMC12340317

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.