Evidence map›Paper›PMID 40809204›Full record

ArticleJournal of thoracic disease2025

Association of throat sensation severity with quality of life in patients with chronic cough.

Youngsang Yoo, Ha-Kyeong Won, Eun-Jung Jo, Seung-Eun Lee, Noeul Kang, Byung-Jae Lee, Sae-Hoon Kim, Sang-Heon Kim, Sang-Hoon Kim, Ji-Su Shim and 14 more

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Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Youngsang YooDepartment of Allergy and Clinical Immunology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.
Ha-Kyeong WonDepartment of Internal Medicine, Veterans Health Service Medical Center, Seoul, Korea.
Eun-Jung JoDepartment of Internal Medicine, School of Medicine, Pusan National University, Busan, Korea.
Seung-Eun LeeDepartment of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
Noeul KangDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Byung-Jae LeeDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sae-Hoon KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Sang-Heon KimDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Sang-Hoon KimDepartment of Internal Medicine, Eulji University College of Medicine, Seoul, Korea.
Ji-Su ShimDepartment of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
Min-Hye KimDepartment of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
Sung-Yoon KangDepartment of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Jin AnDepartment of Pulmonary, Allergy and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Korea.
Han-Ki ParkDivision of Allergy and Clinical Immunology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Korea.
Byung-Keun KimDivision of Pulmonology, Allergy and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Young-Chan KimDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Ji-Hyang LeeDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Mi-Yeong KimDepartment of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Ji-Yoon OhDivision of Allergy, Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.
Kyung-Eun ParkUniversity of Ulsan College of Medicine, Seoul, Korea.
Yeonhee KimDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Joon-Woo BahnDepartment of Convergence Medicine, Asan Medical Center, Seoul, Korea.
Hwa Young LeeDivision of Allergy, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with chronic cough frequently present with abnormal throat sensations, but the clinical significance of such sensations remains unknown. This study examined the severity of throat sensations and their relationships with quality of life (QoL) in patients with chronic cough. Methods: The analysis used baseline cross-sectional data from the Korean Chronic Cough Registry. Throat sensation and cough severity were assessed using visual analog scales (VAS, 0-100) and were categorized into tertiles. Demographics and patient-reported outcomes were compared across the throat sensation severity tertiles. Cough-specific QoL was assessed using the Leicester Cough Questionnaire (LCQ). General health-related QoL was assessed using the standardized EuroQoL 5-Dimension (EQ-5D) instrument. Results: A total of 649 patients with chronic cough (females: 68.1%) with a mean age of 54.7 years were enrolled. Throat sensation severity VAS scores moderately correlated with cough VAS scores (r=0.469, P<0.001). Patients with more severe throat sensations (tertile 3) were younger and had more concomitant symptom and cough-induced complications than those with less severe throat sensations (tertile 1) (P<0.001). Multivariate regression analysis demonstrated that throat sensation severity remained significantly associated with LCQ score and EQ-5D index, after adjusting for confounders, including cough severity (all P<0.05). Conclusions: Abnormal throat sensation may independently contribute to impaired QoL in patients with chronic cough, and its longitudinal impact warrants investigation.

Indexed as

Chronic coughglobus sensationquality of life (QoL)

Identifiers

PMID40809204
PMCPMC12340281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.