ArticleFrontiers in oncology2025
Assessment of the imaging quality and heterogeneous predictive value of readout-segmented echo planar imaging for diffusion-weighted rectal MRI.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To qualitatively and quantitatively compare the image quality of readout-segmented echo planar imaging (rs-EPI) and single-shot echo planar imaging (ss-EPI) for diffusion-weighted (DWI) rectal MRI, as well as the heterogeneous predictive value of the apparent diffusion coefficient (ADC) values obtained by the two DWI techniques. Methods: The rs-EPI and ss-EPI images were subjectively assessed for lesion sharpness, display of normal structure, overall image quality, geometric distortion, and anatomical differences. The signal-to-noise ratio (SNR), contrast ratio (CR), contrast-to-noise ratio (CNR), and ADC values were objectively compared. Pearson's correlations and ROC analysis were used to explore the relationships of ADC values obtained by the two techniques and nucleus related antigen (Ki-67) and hypoxia inducible factor-1α (HIF-1α). Results: Eighty patients with rectal cancer (RC) were included. Lesion sharpness, normal structure display, overall image quality, geometric distortion and anatomical structure differences in the rs-EPI DWI group were higher than in the ss-EPI DWI group ( Conclusion: rs-EPI DWI can improve image quality and the ADC value is associated with pathologic markers of tumor aggression.
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