Evidence map›Paper›PMID 40808842›Full record

ArticleFrontiers in nutrition2025

Association between body roundness index and advanced cardiovascular-kidney-metabolic syndrome.

Yuehui Chen, Hongxiang Tu, Min Liang, Mo Shen

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuehui ChenDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Hongxiang TuDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Min LiangDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Mo ShenDepartment of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular-kidney-metabolic (CKM) syndrome is a disease characterized by interrelated cardiovascular, renal, and metabolic abnormalities. The body roundness index (BRI) is an innovative anthropometric index that characterizes human body shape by calculating body roundness and using eccentricity to estimate visceral and total body fat percentages. The present study aimed to clarify the relation between BRI and advanced CKM syndrome. Methods: Data were obtained from the National Health and Nutrition Examination Survey conducted between 2005 and 2018. Tertiles based on data analysis were applied to divide the levels of BRI. Regression methods assessed the association of BRI with the risk of advanced CKM syndrome. Moreover, receiver operating characteristic analysis determined BRI's predictive performance for such a syndrome. Results: The present study included 12,329 participants, with an advanced CKM occurrence rate of 12.20%. Regression analysis revealed a positive association between BRI and advanced CKM syndrome. After adjusting for covariates, individuals in the highest BRI tertile (T3) showed a significantly higher prevalence of advanced CKM syndrome compared to the reference group (odds ratio: 1.49; 95% confidence interval: 1.09-2.03, Conclusion: An increased BRI is associated with a higher occurrence rate of advanced CKM syndrome. BRI demonstrated a stronger correlation with advanced CKM than traditional measures and warrants consideration as a preferred metric for CKM risk stratification.

Indexed as

body roundness indexCKMNHANESobesityRCS

Identifiers

PMID40808842
PMCPMC12343269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.