Evidence map›Paper›PMID 40808822›Full record

ReviewJHLT open2025

Rare but serious: pulmonary vascular disease around the world.

Clara Hjalmarsson, Arun Jose, Hooman Poor, Camila M C Loureiro, Valentina Stosor, Tomas Pulido, Mrinalini Krishnan

Abstract readReview
In one paragraph

Review in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clara HjalmarssonDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Arun JoseDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati, Cincinnati, OH.
Hooman PoorDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Camila M C LoureiroPulmonary Medicine, Santa Casa da Bahia, Salvador, BA, Brazil.
Valentina StosorNorthwestern University Feinberg School of Medicine, Chicago, IL.
Tomas PulidoIgnacio Chavez National Heart Institute, Mexico City, Mexico.
Mrinalini KrishnanMedStar Heart and Vascular Institute / Georgetown University School of Medicine, Washington, DC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH), a subtype of pulmonary hypertension (PH) classified under Group 1 of the World Health Organization (WHO) classification, is a progressive disorder characterized by pulmonary vascular remodeling, increased pulmonary vascular resistance, and eventual right heart failure. While common etiologies are well described, less frequent causes are often underrecognized, despite their potential impact on prognosis and therapeutic decision-making. During the April 2025 International Society of Heart and Lung Transplantation (ISHLT) annual meeting in Boston, USA, a dedicated symposium entitled "Rare but Serious: Pulmonary Vascular Disease Around the World" addressed these overlooked forms of pulmonary vascular disease (PVD). This review summarizes the latest diagnostic and therapeutic insights into several rare but clinically significant entities, including portopulmonary hypertension (PoPH), PH associated with hematologic disorders, HIV-associated PAH, high-altitude PH and PAH, and schistosomiasis-associated PAH (Sch-PAH). Raising awareness and understanding of these conditions is critical to ensuring timely diagnosis, personalized treatment, and improved patient outcomes.

Indexed as

Chronic hemolytic anemia associated PHHigh-altitude PHHIV-PAHPortopulmonary hypertensionSchistosoma-associated PAH

Identifiers

PMID40808822
PMCPMC12345328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.