Evidence map›Paper›PMID 40808799›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2025

Semi-stationary Multi-source AI-powered Real-time Tomography.

Weiwen Wu, Yaohui Tang, Tianling Lv, Wenxiang Cong, Chuang Niu, Cheng Wang, Yiyan Guo, Peiqian Chen, Yunheng Chang, Ge Wang and 1 more

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Weiwen WuSchool of Biomedical Engineering, Sun-Yat Sen University, Shenzhen, Guangdong China.
Yaohui TangSchool of Biomedical Engineering, Shanghai Jiaotong University, Shanghai, China.
Tianling LvJiangsu First-Imaging Medical Equipment Co., Ltd., Jiangsu, China.
Wenxiang CongDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
Chuang NiuDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
Cheng WangSchool of Biomedical Engineering, Shanghai Jiaotong University, Shanghai, China.
Yiyan GuoSchool of Biomedical Engineering, Shanghai Jiaotong University, Shanghai, China.
Peiqian ChenSchool of Biomedical Engineering, Shanghai Jiaotong University, Shanghai, China.
Yunheng ChangJiangsu First-Imaging Medical Equipment Co., Ltd., Jiangsu, China.
Ge WangDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
Yan XiJiangsu First-Imaging Medical Equipment Co., Ltd., Jiangsu, China.

Funding

THE DETERMINANTS OF MUTATIONP01CA023767 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI AXEL, RICHARD · 1985 to 2008
$8.3M
Cardiac CT DebloomingR01HL151561 · NHLBI · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI BUDOFF, MATTHEW J, DE MAN, BRUNO · 2020 to 2023
$3.8M
Constrained Disentanglement (CODE) Network for CT Metal Artifact Reduction in Radiation TherapyR01EB031102 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI DE MAN, BRUNO, PAGANETTI, HARALD · 2021 to 2021
$2.6M
Adversarially Based Virtual CT Workflow for Evaluation of AI in Medical ImagingR01EB032716 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI JIA, XUN, MUELLER, KLAUS · 2022 to 2025
$2.5M
SPECT with a Compton Camera for Thyroid Cancer ImagingR21CA264772 · NCI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI WANG, GE, YU, HENGYONG · 2021 to 2021
$408k
NCI NIH HHS P01 CA023767NCI NIH HHS R21 CA264772NHLBI NIH HHS R01 HL151561NIBIB NIH HHS R01 EB031102NIBIB NIH HHS R01 EB032716
6 · The paper itself

Abstract

Over the past decades, the development of CT technologies has been largely driven by the need for cardiac imaging but the temporal resolution remains insufficient for clinical CT in difficult cases and rather challenging for preclinical CT since small animals have much higher heart rates than humans. To address this challenge, here we report a Semi-stationary Multi-source AI-based Real-time Tomography (SMART) CT system. This unique scanner is featured by 29 source-detector pairs fixed on a circular track to collect X-ray signals in parallel, enabling instantaneous tomography in principle. Given the multisource architecture, the field-of-view only covers a cardiac region. To solve the interior problem, an AI-empowered interior tomography approach is developed to synergize sparsity-based regularization and learning-based reconstruction. To demonstrate the performance and utilities of the SMART system, extensive results are obtained in physical phantom experiments and animal studies, including dead and live rats as well as live rabbits. The reconstructed volumetric images convincingly demonstrate the merits of the SMART system using the AI-empowered interior tomography approach, enabling cardiac CT with the unprecedented temporal resolution of 33ms, which enjoys the highest temporal resolution than the state of the art.

Indexed as

cardiac imagingComputed tomography (CT)deep learningimage reconstructionmulti-sourcepreclinical imagingreal-time

Identifiers

PMID40808799
PMCPMC12341843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.