Evidence map›Paper›PMID 40808578›Full record

SynthesisFuture cardiology2025

Acute myocardial infarction treatment delay in South Asia: a systematic review and meta-analysis.

Deepthi Ramamurthy, Meely Panda, Manjula Rangappa, Suthanthira Kannan, Rashmi Kundapur, Swetha Rajeshwari, Padmavathi Subbiah, Pradeep Aggarwal, Sumit Aggarwal

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Future cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deepthi RamamurthyDepartment of Community Medicine, ESIC MC & PGIMSR, Bengaluru, India.
Meely PandaDepartment of Community Medicine & Family Medicine, AIIMS Bibinagar, Hyderabad, India.
Manjula RangappaDepartment of Community Medicine, S Nijalingappa Medical College, Bagalkot, India.
Suthanthira KannanDepartment of Community Medicine, ESIC Medical College and Hospital, Chennai, India.
Rashmi KundapurDepartment of Community Medicine & Family Medicine, AIIMS Bibinagar, Hyderabad, India.
Swetha RajeshwariAll India Institute of Hygiene and Public Health, Bidhannaga, India.
Padmavathi SubbiahDepartment of Community Medicine, ESIC Medical College and Hospital, Chennai, India.
Pradeep AggarwalDepartment of Community Medicine & Family Medicine, AIIMS, Rishikesh, India.
Sumit AggarwalDivision of Descriptive Research, Indian Council of Medical Research- Hqrs, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute Myocardial Infarction (AMI) necessitates timely treatment to improve outcomes. Identifying treatment delays across different South Asian countries can aid in formulating policies to reduce these delays. Objectives: To estimate the average treatment delay in AMI patients in South Asia and identify contributing factors.

methodsUsing the CoCoPop framework (Condition, Context, Population), studies were reviewed on AMI treatment delays in South Asia from 2000 to 2022. Databases searched included PubMed Central, Embase and Google Scholar. Eligible studies were cross-sectional and analytical that reported exact delay times, excluding knowledge, attitude, practice studies, narrative reviews, and case reports.

resultsThe search yielded 2954 records, with 42 studies meeting the inclusion criteria. The pooled median prehospital delay was 531 minutes (95% CI: 366-769 minutes). The pooled mean door-to-ECG time was 9.18 minutes (95% CI: 2.52-15.84 minutes). The door-to-needle and door to balloon time among STEMI patients were 37.95 (95% CI: 30.11-45.78 minutes) minutes and 62.92 minutes (95% CI: 45.28-80.56 minutes), respectively with significant heterogeneity. Factors associated with delays included old age, female gender, low literacy, ignorance, financial constraints, and rural location.

conclusionSignificant treatment delays for AMI patients in South Asia are identified, with socio-economic and logistical barriers contributing to these delays.

Indexed as

Myocardial InfarctionTime-to-TreatmentAsiaAsia, SouthernHumansTreatment Delayacute coronary syndromemyocardial infarctionSouth AsiaSTEMISTROBETime-to-treatmenttreatment delay

Identifiers

PMID40808578
PMCPMC12645899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.