Evidence map›Paper›PMID 40808557›Full record

ArticleAnimal bioscience2025

Effects of zilpaterol hydrochloride and virginiamycin on growth performance, carcass characteristics, and visceral organ mass in feedlot lambs.

Mario Alejandro Mejía Delgadillo, Karla Hildeliza Leyva Medina, Jaime Noe Sánchez Pérez, Héctor Aarón Lee Rangel, Hugo de Jesús López Inzunza, Roberto Martínez León, Gamaliel Molina Gámez, José Luis Ponce Covarrubias, Horacio Dávila Ramos, Juan Carlos Robles Estrada

Abstract read
In one paragraph

Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Blend of Essential Oils Plus Vitamin D3 Combined withAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mario Alejandro Mejía DelgadilloFacultad de Agronomía, Universidad Autónoma de Sinaloa, Culiacán, México.
Karla Hildeliza Leyva MedinaFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Sinaloa, Culiacán, México.
Jaime Noe Sánchez PérezFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Sinaloa, Culiacán, México.
Héctor Aarón Lee RangelFacultad de Agronomía y Veterinaria, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Hugo de Jesús López InzunzaFacultad de Agronomía, Universidad Autónoma de Sinaloa, Culiacán, México.
Roberto Martínez LeónFacultad de Agronomía, Universidad Autónoma de Sinaloa, Culiacán, México.
Gamaliel Molina GámezFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Sinaloa, Culiacán, México.
José Luis Ponce CovarrubiasEscuela Superior de Medicina Veterinaria y Zootecnia No. 3, Universidad Autónoma de Guerrero, Técpan de Galeana, México.
Horacio Dávila RamosFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Sinaloa, Culiacán, México.
Juan Carlos Robles EstradaFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Sinaloa, Culiacán, México.

Funding

research project promotion and support program PROFAPI 2022Universidad Autónoma de Sinaloa PRO_A7_055
6 · The paper itself

Abstract

objectiveThe objective was to determine the effect of dietary zilpaterol hydrochloride and virginiamycin on growth performance, dietary energetics, carcass characteristics, and visceral organ mass in feedlot lambs.

methodsThirty-two crossbred lambs Dorper×Katahdin (34.04±4.23 kg), five months old, were used in a 30 d experiment to evaluate the inclusion of zilpaterol and virginiamycin. Treatments were randomly assigned to pens within blocks, with four replicates per treatment. Data were analyzed as a randomized complete block design arranged as 2×2 factorial, with two levels of zilpaterol (0 and 0.20 mg/kg of live weight/d, as hydrochloride form) and two levels of virginiamycin (0 and 22 mg/lamb/d). The diet was based on cracked corn (1.41 Mcal NEg/kg of dry matter and 14.1% of crude protein). Growth performance and dietary energetics variables were recorded. After the feeding trial, lambs were transported to a slaughterhouse for assessment of carcass characteristics, visceral organ mass, and primal cuts.

resultsNo interactions were observed between zilpaterol and virginiamycin treatments for most of the evaluated variables, except for the percentage of the empty small intestine. Lambs supplemented with both zilpaterol and virginiamycin showed improvements in live weight, feed efficiency, and energy retention. However, only zilpaterol affected dressing percentage, longissimus thoracis muscle, and body fat reduction. The combined supplementation increased final live weight without altering feed intake, thereby enhancing energy availability to promote carcass weight and dressing carcass compared to lambs treated with zilpaterol alone.

conclusionZilpaterol hydrochloride (0.20 mg/kg of live weight/d, equivalent to 7.55 mg/lamb/d) and virginiamycin (22 mg/lamb/d) improved growth and energy retention, but only zilpaterol improved dressing percentage and reduced fat traits of carcass and non-carcass components. The effects of virginiamycin and zilpaterol were found to be cumulative, with better responses in growth and dietary energy components observed in lambs supplemented with both additives.

Indexed as

Carcass CharacteristicsGrowth PerformanceLambsVirginiamycinZilpaterol

Identifiers

PMID40808557
PMCPMC12580932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.