Evidence map›Paper›PMID 40808543›Full record

ReviewNanomedicine (London, England)2025

Therapeutic opportunities for nanomedicine with hollow one-dimensional silicon nanotubes.

Nguyen T Le, Jeffery L Coffer

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nguyen T LeResearch and Development, Advanced Silicon Group, Lowell, MA, USA.
Jeffery L CofferDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, TX, USA.

Funding

Robert A. Welch Foundation
6 · The paper itself

Abstract

While perhaps best known for its role in the semiconductor device industry, silicon at the nanoscale is drawing extensive attention to biotech applications such as drug delivery as a consequence of structural diversity and biomedically useful properties. In this focused review we specifically center on one-dimensional nanotubes of silicon by first discussing fabrication routes and then cover fundamental studies of silicon-based nanotube structures relevant to applications in non-traditional platinate chemotherapy as well as gene therapy. Two types of basic platforms are described: (1) freestanding nanotube bundles as well as (2) patterned arrays. Our emphasis here is with regard to tunability of structure tailored to a given application. We conclude with a discussion of existing challenges and opportunities for the future.

Indexed as

NanomedicineNanotubesSiliconAnimalsDrug Delivery SystemsGenetic TherapyHumansSiliconchemotherapydrug deliverynanotubesSiliconsiRNA

Identifiers

PMID40808543
PMCPMC12490400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.