Evidence map›Paper›PMID 40808350›Full record

ReviewInternational journal of molecular medicine2025

Noncoding RNAs in periodontitis: Progress and perspectives (Review).

Yuanyi Feng, Xiaolan Guo, Yumeng Yang, Wei Qiu, Zhao Chen, Fuchun Fang

Abstract readReview
In one paragraph

Review in International journal of molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Non-Coding RNAs in Oral Diseases: From Pathogenesis to Clinical Translation.International journal of molecular sciences · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuanyi FengStomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Xiaolan GuoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Yumeng YangStomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Wei QiuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Zhao ChenDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Fuchun FangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is the sixth most common chronic non‑infectious disease in the world. It mainly leads to the inflammatory destruction of periodontal supporting tissue, which has become the main cause of tooth loss in adults. Periodontitis is also a risk factor for various systemic diseases. Noncoding ribonucleic acids (ncRNAs) are important regulators of normal biological processes and their abnormal expression has been shown to be important to the pathogenesis of inflammatory diseases, including periodontitis. Biologically, they can regulate immune inflammation, bone homeostasis and cell proliferation in periodontitis. Clinically, they are promising diagnostic markers and therapeutic targets. Recent advances in technology have opened up new directions for the study of ncRNAs, including RNA secondary structures, RNA protein interactions, ncRNA‑encoded peptides or proteins and single‑cell RNA sequencing. Therefore, the present study summarized the function and mechanisms of ncRNAs in periodontitis, as well as their clinical potential for diagnosis and treatment and highlight these exciting areas of research.

Indexed as

PeriodontitisRNA, UntranslatedAnimalsBiomarkersHumansBiomarkersRNA, Untranslatedcircular RNAlong noncoding RNAnoncoding RNAperiodontitistherapeutics

Identifiers

PMID40808350
PMCPMC12373436

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.