Evidence map›Paper›PMID 40808280›Full record

ArticleMagnetic resonance in medicine2025

Dynamic contrast enhanced-magnetic resonance fingerprinting (DCE-MRF): A new quantitative MRI method to reliably assess tumor vascular perfusion.

Christina J MacAskill, Yuran Zhu, Guanhua Wang, Bernadette O Erokwu, Chetan B Dhakan, Andrew Dupuis, Barbara J Schiemann, Michael Kavran, Chunying Wu, William P Schiemann and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christina J MacAskillDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-0023-0044
Yuran ZhuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-2829-7451
Guanhua WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-1622-5664
Bernadette O ErokwuDepartment of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
Chetan B DhakanDepartment of Medical Physics, University of Wisconsin, Madison, Wisconsin, USA.
Andrew DupuisDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-3714-4812
Barbara J SchiemannCase Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA.
Michael KavranDepartment of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
Chunying WuDepartment of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
William P SchiemannCase Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-0338-2636
Mark A GriswoldDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-3011-6747
Xin YuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-8996-0267
Mark D PagelDepartment of Medical Physics, University of Wisconsin, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-8109-3995
Chris A FlaskDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-1066-333X

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
NRSA Training CoreTL1TR002549 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI HARDING, CLIFFORD V · 2018 to 2022
$2.9M
AQP4 and glymphatic function in post-stroke recoveryR01NS124206 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI Christopher A Flask, Xin Yu · 2022 to 2026
$2.8M
Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and AcidosisR01CA269354 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Christopher A Flask, Mark David Pagel · 2023 to 2026
$2.6M
PET Insert for Preclinical PET-MRIS10OD030499 · OD · CASE WESTERN RESERVE UNIVERSITY · PI FLASK, CHRISTOPHER A · 2021 to 2021
$413k
American Heart Association 23PRE1017924NCATS NIH HHS LR1 TR002549NCATS NIH HHS TL1 TR002549NCATS NIH HHS UM1 TR004528NCI NIH HHS P30 CA043703NCI NIH HHS R01 CA269354NIGMS NIH HHS T32 GM007250NIH HHS S10 OD030499NINDS NIH HHS R01 NS124206
6 · The paper itself

Abstract

purposeThe clinical utility of conventional DCE-MRI methods is limited by the use of conventional qualitative dynamic T

methodsThe DCE-MRF acquisition combines multiple T

resultsIn vitro DCE-MRF studies demonstrated good agreement with conventional MRI methods for T

conclusionsDCE-MRF represents a new inherently quantitative approach to measuring tumor vascular perfusion that can be used in animal models and eventually in patients.

Indexed as

Breast NeoplasmsContrast MediaMagnetic Resonance AngiographyMagnetic Resonance ImagingNeovascularization, PathologicAnimalsCell Line, TumorFemaleHumansImage Processing, Computer-AssistedMiceMice, Inbred BALB CReproducibility of ResultsContrast Mediabreast cancerdynamic contrast‐enhancedmouse modelsMR fingerprintingpharmacokinetic modeling

Identifiers

PMID40808280
PMCPMC12501753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.