Evidence map›Paper›PMID 40808155›Full record

ArticlePolymers2025

Emodin-Loaded Thermoresponsive Hydrogel as a Potential Drug Delivery System for Periodontal Disease in a Rat Model of Ligature-Induced Periodontitis.

Gyu-Yeon Shim, Seong-Hee Moon, Seong-Jin Shin, Hyun-Jin Kim, Seunghan Oh, Ji-Myung Bae

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gyu-Yeon ShimDepartment of Dental Biomaterials, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Seong-Hee MoonInstitute of Biomaterials and Implant, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Seong-Jin ShinDepartment of Dental Biomaterials, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.ORCID 0000-0002-4140-5157
Hyun-Jin KimInstitute of Biomaterials and Implant, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Seunghan OhDepartment of Dental Biomaterials, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.ORCID 0000-0002-7250-721X
Ji-Myung BaeDepartment of Dental Biomaterials, College of Dentistry, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.ORCID 0000-0002-8607-8604

Funding

National Research Foundation of Korea (NRF) grant funded by the Korean Government (MSIT) RS-2021-NR058416
6 · The paper itself

Abstract

Periodontitis, a chronic inflammatory disease, causes alveolar bone loss. Current treatments show limitations in achieving dual antimicrobial and anti-inflammatory effects. We evaluated an emodin-loaded thermoresponsive hydrogel as a local drug delivery system for periodontitis treatment. Emodin itself demonstrated antibacterial activity against

Indexed as

antibacterialanti-inflammatoryemodinlocal drug deliveryperiodontitisthermoresponsive hydrogel

Identifiers

PMID40808155
PMCPMC12349398

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.