Evidence map›Paper›PMID 40807978›Full record

ArticleSensors (Basel, Switzerland)2025

Running-Induced Fatigue Exacerbates Anteromedial ACL Bundle Stress in Females with Genu Valgum: A Biomechanical Comparison with Healthy Controls.

Xiaoyu Jian, Dong Sun, Yufan Xu, Chengyuan Zhu, Xuanzhen Cen, Yang Song, Gusztáv Fekete, Danica Janicijevic, Monèm Jemni, Yaodong Gu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoyu JianFaculty of Sports Science, Ningbo University, Ningbo 315211, China.
Dong SunFaculty of Sports Science, Ningbo University, Ningbo 315211, China.ORCID 0000-0002-7634-5668
Yufan XuFaculty of Sports Science, Ningbo University, Ningbo 315211, China.
Chengyuan ZhuFaculty of Sports Science, Ningbo University, Ningbo 315211, China.
Xuanzhen CenFaculty of Sports Science, Ningbo University, Ningbo 315211, China.ORCID 0000-0003-4189-7670
Yang SongDepartment of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0001-7438-6290
Gusztáv FeketeDepartment of Material Science and Technology, Audi Hungaria Faculty of Automotive Engineering, Széchenyi István University, 9026 Győr, Hungary.ORCID 0000-0002-6138-8382
Danica JanicijevicDepartment of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-9925-7751
Monèm JemniCentre for Mental Health Research in Association with the University of Cambridge, Cambridge CB2 1TN, UK.
Yaodong GuFaculty of Sports Science, Ningbo University, Ningbo 315211, China.ORCID 0000-0003-2187-9440

Funding

K. C. Wong Magna Fund in Ningbo UniversityNational Key R&D Program of China 2024YFC3607305Ningbo Clinical Research Center for Orthopedics and Exercise Rehabilitation No.2024L004Ningbo Key Research and Development Program 2022Z196Ningbo Natural Science Foundation 2022J065Research Academy of Medicine Combining Sports, Ningbo No.2023001Zhejiang Engineering Research Center for New Technologies and Applications of Helium-Free Magnetic Resonance Imaging Open Fund Project 2024 2024GCPY02Zhejiang Province Science Fund for Distinguished Young Scholars LR22A020002Zhejiang Provincial Key Project of Education Science Planning 2025SB084Zhejiang Rehabilitation Medical Association Scientific Research Special Fund ZKKY2023001
6 · The paper itself

Abstract

Genu valgum (GV) is a common lower limb deformity that may increase the risk of anterior cruciate ligament (ACL) injury. This study used OpenSim musculoskeletal modeling and kinematic analysis to investigate the mechanical responses of the ACL under fatigue in females with GV. Eight females with GV and eight healthy controls completed a running-induced fatigue protocol. Lower limb kinematic and kinetic data were collected and used to simulate stress and strain in the anteromedial ACL (A-ACL) and posterolateral ACL (P-ACL) bundles, as well as peak joint angles and knee joint stiffness. The results showed a significant interaction effect between group and fatigue condition on A-ACL stress. In the GV group, A-ACL stress was significantly higher than in the healthy group both before and after fatigue (

Indexed as

Anterior Cruciate LigamentFatigueGenu ValgumRunningAdultAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaFemaleHumansKnee JointStress, MechanicalYoung Adultanterior cruciate ligamentgenu valgumknee modelstrainstress

Identifiers

PMID40807978
PMCPMC12349260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.