Recording of Cardiac Excitation Using a Novel Magnetocardiography System with Magnetoresistive Sensors Outside a Magnetic Shielded Room.

Magnetocardiography (MCG) provides a non-invasive, contactless technique for evaluating the magnetic fields generated by cardiac electrical activity, offering unique spatial insights into cardiac electrophysiology. However, conventional MCG systems depend on superconducting quantum interference devices that require cryogenic cooling and magnetic shielded environments, posing considerable impediments to widespread clinical adoption. In this study, we present a novel MCG system utilizing a high-sensitivity, wide-dynamic-range magnetoresistive sensor array operating at room temperature. To mitigate environmental interference, identical sensors were deployed as reference channels, enabling adaptive noise cancellation (ANC) without the need for traditional magnetic shielding. MCG recordings were obtained from 40 healthy participants, with signals processed using ANC, R-peak-synchronized averaging, and Bayesian spatial signal separation. This approach enabled the reliable detection of key cardiac components, including P, QRS, and T waves, from the unshielded MCG recordings. Our findings underscore the feasibility of a cost-effective, portable MCG system suitable for clinical settings, presenting new opportunities for noninvasive cardiac diagnostics and monitoring.