Evidence map›Paper›PMID 40807368›Full record

ArticleMolecules (Basel, Switzerland)2025

Semi-Synthesis, Anti-Leukemia Activity, and Docking Study of Derivatives from 3

Mario J Noh-Burgos, Sergio García-Sánchez, Fernando J Tun-Rosado, Antonieta Chávez-González, Sergio R Peraza-Sánchez, Rosa E Moo-Puc

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mario J Noh-BurgosUnidad de Biotecnología, Centro de Investigación Científica de Yucatán (CICY), Mérida 97205, Mexico.ORCID 0009-0002-9453-6262
Sergio García-SánchezUnidad de Investigación Médica en Enfermedades Oncológicas, UMAE Hospital de Oncología, Centro Médico Nacional Siglo XXI, IMSS, Ciudad de México 06720, Mexico.
Fernando J Tun-RosadoInstituto de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Antonieta Chávez-GonzálezUnidad de Investigación Médica en Enfermedades Oncológicas, UMAE Hospital de Oncología, Centro Médico Nacional Siglo XXI, IMSS, Ciudad de México 06720, Mexico.ORCID 0000-0002-4542-1023
Sergio R Peraza-SánchezUnidad de Biotecnología, Centro de Investigación Científica de Yucatán (CICY), Mérida 97205, Mexico.ORCID 0000-0002-8161-501X
Rosa E Moo-PucSecretaría de Ciencia, Humanidades, Tecnología e Innovación-Hospital Regional de Alta Especialidad de la Península de Yucatán, IMSS-BIENESTAR, Mérida 97130, Mexico.ORCID 0000-0001-9204-6062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current treatments against leukemia present several limitations, prompting the search for new therapeutic agents, particularly those derived from natural products. In this context, structural modifications were performed on the triterpene 3

Indexed as

Antineoplastic AgentsLeukemiaMolecular Docking SimulationTriterpenesApoptosisCell Line, TumorCell ProliferationCell SurvivalErbB Receptorsfms-Like Tyrosine Kinase 3HumansProto-Oncogene Proteins c-bcl-2Structure-Activity RelationshipAntineoplastic AgentsErbB Receptorsfms-Like Tyrosine Kinase 3Proto-Oncogene Proteins c-bcl-2Triterpenesapoptosisdocking studiesleukemiapentacyclic lupane-type triterpenes

Identifiers

PMID40807368
PMCPMC12348585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.