Pinene-Based Chiral Bipyridine Ligands Drive Potent Antibacterial Activity in Rhenium(I) Complexes.

Justine Horner, Gozde Demirci, Aurelien Crochet, Aleksandar Pavic, Olimpia Mamula Steiner, Fabio Zobi

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Synthesis, Characterization, and Biological Evaluation of Co(II), Cu(II), and Ni(II) Complexes With 2,2'-Bipyridine-5,5'-Dicarboxamide Ligands: Antibacterial and Enzyme Inhibition Studies.ChemistryOpen · 2026
Article
Synthesis, Characterization, and Biological Evaluation of Noble Metal Complexes with 2‑(1-Benzyl‑1ACS omega · 2026
Article
Iron(II) and Manganese(II) Complexes with N4Py as Dioxygen Activators for α-Pinene Oxidation in Acetonitrile.Molecules (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Justine HornerDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland.ORCID 0009-0002-8739-8586

Gozde DemirciDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland.ORCID 0000-0003-4952-7981

Aurelien CrochetDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland.ORCID 0000-0002-4763-2764

Aleksandar PavicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia.ORCID 0000-0003-3233-1341

Olimpia Mamula SteinerHaute Ecole d'Ingénierie et d'Architecture Fribourg, HEIA-FR, HES-SO, Institute of Chemical Technology, University of Applied Sciences of Western Switzerland, Pérolles 80, CH-1705 Fribourg, Switzerland.ORCID 0000-0002-3538-3553

Fabio ZobiDepartment of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland.ORCID 0000-0002-9077-7184

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) poses a critical global health threat by rendering existing antibiotics ineffective against infections, leading to increased mortality, prolonged illnesses, and higher healthcare costs. Developing new antibiotics is essential to combat resistant pathogens, safeguard modern medical procedures, and prevent a return to a pre-antibiotic era where common infections become untreatable. We report a series of chiral tricarbonyl rhenium(I) complexes incorporating enantiopure pinene-substituted bipyridine ligands (L#) of the general formula

Indexed as

2,2'-DipyridylAnti-Bacterial AgentsCoordination ComplexesPyridinesRheniumHumansLigandsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStereoisomerismStructure-Activity Relationship2,2'-DipyridylAnti-Bacterial AgentsCoordination ComplexesLigandsPyridinesRheniumantimicrobialchiralpinenerheniumtricarbonyl

Identifiers

PMID40807357

DOI10.3390/molecules30153183

PMCPMC12348105

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.