Evidence map›Paper›PMID 40807355›Full record

ReviewMolecules (Basel, Switzerland)2025

Nano-Phytomedicine: Harnessing Plant-Derived Phytochemicals in Nanocarriers for Targeted Human Health Applications.

Nargish Parvin, Mohammad Aslam, Sang Woo Joo, Tapas Kumar Mandal

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nargish ParvinSchool of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0002-1209-1507
Mohammad AslamSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Sang Woo JooSchool of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0002-3694-6813
Tapas Kumar MandalSchool of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0003-2615-8618

Funding

NRFK NRF-2019R1A5A8080290
6 · The paper itself

Abstract

Phytochemicals from medicinal plants offer significant therapeutic benefits, yet their clinical utility is often limited by poor solubility, instability, and low bioavailability. Nanotechnology presents a transformative approach to overcome these challenges by encapsulating phytochemicals in nanocarriers that enhance stability, targeted delivery, and controlled release. This review highlights major classes of phytochemicals such as polyphenols, flavonoids, and alkaloids and explores various nanocarrier systems including liposomes, polymeric nanoparticles, and hybrid platforms. It also discusses their mechanisms of action, improved pharmacokinetics, and disease-specific targeting. Further, the review examines clinical advancements, regulatory considerations, and emerging innovations such as smart nanocarriers, AI-driven formulation, and sustainable manufacturing. Nano-phytomedicine offers a promising path toward safer, more effective, and personalized therapies, bridging traditional herbal knowledge with modern biomedical technology.

Indexed as

Drug CarriersNanoparticlesPhytochemicalsAnimalsDrug Delivery SystemsHumansLiposomesPhytotherapyPlants, MedicinalDrug CarriersLiposomesPhytochemicalsnano-phytomedicinephytochemical delivery systemsplant-derived nanotherapeuticsstimuli-responsive nanocarrierstargeted drug delivery

Identifiers

PMID40807355
PMCPMC12348851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.