Amino Acid Substitutions in Bacteriocin Lactolisterin BU Reveal Functional Domains Involved in Biological Activity Against

Lazar Gardijan, Milka Malešević, Miroslav Dinić, Aleksandar Pavić, Nikola Plačkić, Goran Jovanović, Milan Kojić

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Bacteriostatic Mechanism of the Ethyl Acetate Extract from the Root ofVeterinary sciences · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lazar GardijanInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0003-0966-6928

Milka MaleševićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-9769-0471

Miroslav DinićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.

Aleksandar PavićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.

Nikola PlačkićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0009-0005-3466-6841

Goran JovanovićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-6587-7645

Milan KojićInstitute of Virology, Vaccines and Sera "Torlak", 11000 Belgrade, Serbia.ORCID 0000-0001-5645-750X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of multidrug-resistant pathogens has driven the development of novel antimicrobial peptides (AMPs) as therapeutic alternatives. Lactolisterin LBU (LBU) is a bacteriocin with promising activity against Gram-positive bacteria, including

Indexed as

Amino Acid SubstitutionAnti-Bacterial AgentsBacteriocinsStaphylococcus aureusAmino Acid SequenceAnimalsHemolysisHumansMicrobial Sensitivity TestsStructure-Activity RelationshipAnti-Bacterial AgentsBacteriocinsAlphaFoldamino acid substitutionantimicrobial peptidebacteriocinlactolisterin LBUStaphylococcus aureusvirulencezebrafish toxicity

Identifiers

PMID40807309

DOI10.3390/molecules30153134

PMCPMC12348470

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.