Evidence map›Paper›PMID 40807293›Full record

ArticleMolecules (Basel, Switzerland)2025

An Ultrasonication-Assisted Green Process for Simultaneous Production of a Bioactive Compound-Rich Extract and a Multifunctional Fibrous Ingredient from Spent Coffee Grounds.

Jaquellyne B M D Silva, Mayara T P Paiva, Henrique F Fuzinato, Nathalia Silvestre, Marta T Benassi, Suzana Mali

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaquellyne B M D SilvaDepartment of Food Science and Technology, CCA, State University of Londrina, Londrina 86057-970, PR, Brazil.ORCID 0000-0001-8746-0816
Mayara T P PaivaDepartment of Biochemistry and Biotechnology, CCE, State University of Londrina, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-6823-0246
Henrique F FuzinatoDepartment of Biochemistry and Biotechnology, CCE, State University of Londrina, Londrina 86057-970, PR, Brazil.
Nathalia SilvestreDepartment of Biochemistry and Biotechnology, CCE, State University of Londrina, Londrina 86057-970, PR, Brazil.
Marta T BenassiDepartment of Food Science and Technology, CCA, State University of Londrina, Londrina 86057-970, PR, Brazil.ORCID 0000-0003-3448-822X
Suzana MaliDepartment of Biochemistry and Biotechnology, CCE, State University of Londrina, Londrina 86057-970, PR, Brazil.ORCID 0000-0003-4601-1568

Funding

CAPES DSFINEP (01.21.0126.00 - REF. 0128/2021)SETI, Fundação Araucária e Universidade Estadual de Londrina (PROPPG). APC funding
6 · The paper itself

Abstract

Spent coffee grounds (SCGs) are lignocellulosic residues generated from producing espresso or soluble coffee and have no commercial value. This study aimed to develop a new single-step process for extracting bioactive compounds from SCGs based on ultrasonication in an aqueous medium and simultaneously recovering the residual solid fraction, resulting in the integral utilization of the residue. This process resulted in a liquid aqueous extract (LAE) rich in bioactive compounds (caffeine: 400.1 mg/100 g; polyphenols: 800.4 mg GAE/100 g; melanoidins: 2100.2 mg/100 g) and, simultaneously, a solid multifunctional ingredient from modified spent coffee grounds (MSCGs) rich in bioactive compounds and dietary fibers (73.0 g/100 g). The liquid extract can be used as a natural ingredient for drinks or to isolate caffeine, while the solid matrix can be used to produce functional foods. This technique proved to be a promising eco-friendly alternative for the simultaneous production of two different materials from SCGs, maximizing resource efficiency, with some advantages, including short time, simplicity, and cost-effectiveness; using water as a solvent; and requiring no further purification processing.

Indexed as

CoffeeGreen Chemistry TechnologyPlant ExtractsCaffeinePolymersPolyphenolsSonicationCaffeineCoffeemelanoidin polymersPlant ExtractsPolymersPolyphenolsagroindustrial residueantioxidant capacitycaffeinemelanoidins

Identifiers

PMID40807293
PMCPMC12348768

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.