Evidence map›Paper›PMID 40807247›Full record

ArticleMolecules (Basel, Switzerland)2025

Potential Use of Cefiderocol and Nanosilver in Wound Dressings to Control Multidrug-Resistant Gram-Negative Bacteria.

Żaneta Binert-Kusztal, Agata Krakowska, Iwona Skiba-Kurek, Magdalena Luty-Błocho, Anna Kula, Aldona Olechowska-Jarząb, Przemysław Dorożyński, Tomasz Skalski

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Fungal-Derived Chitosan fromMaterials (Basel, Switzerland) · 2025
    Article
  3. Transcriptome analysis ofFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Żaneta Binert-KusztalDepartment of Inorganic Chemistry and Pharmaceutical Analytics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 Street, 30-688 Krakow, Poland.
Agata KrakowskaDepartment of Inorganic Chemistry and Pharmaceutical Analytics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 Street, 30-688 Krakow, Poland.ORCID 0000-0003-3814-3472
Iwona Skiba-KurekDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 Street, 30-688 Krakow, Poland.ORCID 0000-0002-0533-2130
Magdalena Luty-BłochoAGH University of Krakow, Faculty of Non-Ferrous Metals, al. Mickiewicza 30, 30-059 Krakow, Poland.ORCID 0000-0001-9018-7654
Anna KulaAGH University of Krakow, Faculty of Non-Ferrous Metals, al. Mickiewicza 30, 30-059 Krakow, Poland.ORCID 0000-0003-1722-7327
Aldona Olechowska-JarząbDepartment of Microbiology, University Hospital, Marii Orwid 11 Street, 30-680 Krakow, Poland.
Przemysław DorożyńskiDepartment of Inorganic Chemistry and Pharmaceutical Analytics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 Street, 30-688 Krakow, Poland.ORCID 0000-0001-6835-2916
Tomasz SkalskiBiotechnology Centre, Silesian University of Technology, Krzywoustego 8 Street, 44-100 Gliwice, Poland.ORCID 0000-0001-6059-8663

Funding

Jagiellonian University N42/DBS/000397Jagiellonian University N42/DBS/000437
6 · The paper itself

Abstract

This study evaluated the antimicrobial efficacy of cefiderocol and various forms of silver (ionic and nanoparticulate) as potential components of wound-dressing reagents against both reference and multidrug-resistant (MDR) Gram-negative bacteria. The anticipated synergistic effect between cefiderocol and nanosilver was not consistently observed; in fact, for reference strains, the combination was less effective than cefiderocol alone. However, in MDR and cefiderocol-resistant

Indexed as

Anti-Bacterial AgentsBandagesCephalosporinsDrug Resistance, Multiple, BacterialGram-Negative BacteriaMetal NanoparticlesSilverAcinetobacter baumanniiCefiderocolDrug SynergismHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsCefiderocolCephalosporinsSilverAgNPsbacterial infectionscefiderocolGram-negative bacteriasynergysynthesiswounds

Identifiers

PMID40807247
PMCPMC12348696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.