Evidence map›Paper›PMID 40807234›Full record

ArticleMolecules (Basel, Switzerland)2025

One-Pot Synthesis of Phenylboronic Acid-Based Microgels for Tunable Gate of Glucose-Responsive Insulin Release at Physiological pH.

Prashun G Roy, Jiangtao Zhang, Koushik Bhattacharya, Probal Banerjee, Jing Shen, Shuiqin Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prashun G RoyDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.
Jiangtao ZhangDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.ORCID 0009-0006-6232-0941
Koushik BhattacharyaDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.ORCID 0000-0002-3973-2669
Probal BanerjeeDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.ORCID 0000-0001-9429-1010
Jing ShenDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.ORCID 0000-0002-6259-4516
Shuiqin ZhouDepartment of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.ORCID 0000-0003-2257-6150

Funding

Phenylboronic acid-based nanogels for onset-controllable glucose-regulated insulin deliveryR15DK127360 · NIDDK · COLLEGE OF STATEN ISLAND · PI ZHOU, SHUIQIN · 2021 to 2021
$476k
NIDDK-NIH 1R15DK127360-01A1NIDDK NIH HHS R15 DK127360
6 · The paper itself

Abstract

Glucose-responsive insulin delivery systems that effectively regulate insulin retention and release in response to real-time fluctuation of glucose levels are highly desirable for diabetes care with minimized risk of hypoglycemia. Herein, we report a class of glucose-sensitive copolymer microgels, prepared from a simple one-pot precipitation copolymerization of 4-vinylphenylboronic acid (VPBA), 2-(dimethylamino) ethyl acrylate (DMAEA), and oligo(ethylene glycol) methyl ether methacrylate (M

Indexed as

Boronic AcidsGlucoseInsulinMicrogelsDrug LiberationHumansHydrogen-Ion ConcentrationPolymersbenzeneboronic acidBoronic AcidsGlucoseInsulinMicrogelsPolymersgated insulin retention and releasemicrogelsphenyl boronic acidtunable onset of glucose responsivenessvolume phase transition

Identifiers

PMID40807234
PMCPMC12348508

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.