Evidence map›Paper›PMID 40807224›Full record

ArticleJournal of clinical medicine2025

Steady Quiet Asthma Without Biologics: One-Year Outcomes of Single-Inhaler Triple Therapy for Severe Asthma with Small Airway Dysfunction.

Vitaliano Nicola Quaranta, Francesca Montagnolo, Andrea Portacci, Silvano Dragonieri, Maria Granito, Gennaro Rociola, Santina Ferrulli, Leonardo Maselli, Giovanna Elisiana Carpagnano

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07372521 (Measuring Small-Airways Disease Improvement After Step-up to Extrafine TRIple or High-dose ICS/LABA in Patients Uncontrolled on Medium Dose ICS/LABA eXploring T2 Inflammation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07372521 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Measuring Small-Airways Disease Improvement After Step-up to Extrafine TRIple or High-dose ICS/LABA in Patients Uncontrolled on Medium Dose ICS/LABA eXploring T2 Inflammation: The MATRIX Real-life Observational Study

Typeobservational_patient_registrySponsorUniversity Hospital, IoanninaRan2026 to 2028Enrolled130ConditionsAsthma
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. From FEVJournal of asthma and allergy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vitaliano Nicola QuarantaRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Francesca MontagnoloRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Andrea PortacciRespiratory Diseases, University of Bari, 70121 Bari, Italy.ORCID 0000-0002-6127-2486
Silvano DragonieriRespiratory Diseases, University of Bari, 70121 Bari, Italy.ORCID 0000-0003-1563-6864
Maria GranitoRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Gennaro RociolaRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Santina FerrulliRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Leonardo MaselliRespiratory Diseases, University of Bari, 70121 Bari, Italy.
Giovanna Elisiana CarpagnanoRespiratory Diseases, University of Bari, 70121 Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

extrafineinhaled triple therapyquiet asthmasevere asthma

Identifiers

PMID40807224
PMCPMC12347889

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.