Evidence map›Paper›PMID 40807220›Full record

ArticleJournal of clinical medicine2025

Does the Timing of Response Impact the Outcome of Relapsed/Refractory Acute Myeloid Leukemia Treated with Venetoclax in Combination with Hypomethylating Agents? A Proof of Concept from a Monocentric Observational Study.

Ermelinda Longo, Fanny Erika Palumbo, Andrea Duminuco, Laura Longo, Daniela Cristina Vitale, Serena Brancati, Cinzia Maugeri, Marina Silvia Parisi, Giuseppe Alberto Palumbo, Giovanni Luca Romano and 4 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ermelinda LongoHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Fanny Erika PalumboHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.ORCID 0009-0006-4896-6666
Andrea DuminucoHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.ORCID 0000-0002-9510-4755
Laura LongoClinical Pharmacology Program/Regional Pharmacovigilance Centre, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Daniela Cristina VitaleClinical Pharmacology Program/Regional Pharmacovigilance Centre, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.ORCID 0009-0009-4957-958X
Serena BrancatiClinical Pharmacology Program/Regional Pharmacovigilance Centre, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Cinzia MaugeriHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Marina Silvia ParisiHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Giuseppe Alberto PalumboHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.ORCID 0000-0003-1859-6319
Giovanni Luca RomanoDepartment of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.ORCID 0000-0002-8722-7835
Filippo DragoClinical Pharmacology Program/Regional Pharmacovigilance Centre, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Francesco Di RaimondoHematology and Bone Marrow Transplantation Unit, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.
Lucia GozzoClinical Pharmacology Program/Regional Pharmacovigilance Centre, A.O.U. Policlinico "G.Rodolico-S. Marco", 95123 Catania, Italy.ORCID 0000-0002-7512-269X
Calogero VetroHematology and Bone Marrow Transplantation Unit, Hospital of Bolzano (SABES-Azienda Sanitaria dell'Alto Adige), Teaching Hospital of Paracelsus Medical University, 39100 Bolzano, Italy.ORCID 0000-0003-1922-5157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Myeloid Leukemiacytopeniaearly responsehypomethylating Agentslate responserelapsed/refractory AMLresponse ratetreatment related-toxicityvenetoclaxwashout period

Identifiers

PMID40807220
PMCPMC12347298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.