Evidence map›Paper›PMID 40807018›Full record

ReviewJournal of clinical medicine2025

Ophthalmological Complications of Aesthetic Medicine Procedures: A Narrative Review.

Lucía De-Pablo-Gómez-de-Liaño, Fernando Ly-Yang, Bárbara Burgos-Blasco, José Ignacio Fernández-Vigo

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Med Spas: Patient Safety and Accreditation.Aesthetic surgery journal · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucía De-Pablo-Gómez-de-LiañoDepartment of Ophthalmology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
Fernando Ly-YangDepartment of Ophthalmology, Epsom and St Helier NHS University Hospitals, Sutton SM2 5NF, UK.ORCID 0000-0003-4657-4029
Bárbara Burgos-BlascoDepartment of Ophthalmology, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), 28040 Madrid, Spain.ORCID 0000-0003-2178-6164
José Ignacio Fernández-VigoCentro Internacional de Oftalmología Avanzada, 28010 Madrid, Spain.ORCID 0000-0001-8745-3464

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive cosmetic procedures, such as dermal fillers, botulinum toxin injections, autologous fat grafting, intense pulsed light (IPL) treatments, and platelet-rich plasma (PRP) treatments, are increasingly popular worldwide due to their convenience and aesthetic benefits. While generally considered safe, these procedures can result in rare but serious ophthalmological complications. The most catastrophic adverse events include central retinal artery occlusion and ischemic optic neuropathy, which may lead to irreversible vision loss. Other complications include diplopia, ptosis, dry eye, and orbital cellulitis, with varying degrees of severity and reversibility. Awareness of potential ocular risks, appropriate patient selection, and adherence to safe injection techniques are crucial for preventing complications. This narrative review summarizes the incidence, mechanisms, clinical features, risk factors, diagnostic approaches, and management strategies of ocular complications associated with aesthetic medical procedures. A narrative literature review was conducted, emphasizing data from clinical studies, case series, and expert consensus published between 2015 and 2025. Special attention is given to anatomical danger zones, the pathophysiological pathways of filler embolization, and the roles of hyaluronidase and hyperbaric oxygen therapy in acute management. Although many complications are self-limited or reversible, prompt recognition and intervention are critical to prevent permanent sequelae. The increasing prevalence of these procedures demands enhanced education, informed consent, and interdisciplinary collaboration between aesthetic providers and ophthalmologists.

Indexed as

aesthetic medicinebotulinum toxin injectionscosmetic proceduresdermal fillersophthalmological complicationsretinal vascular occlusion

Identifiers

PMID40807018
PMCPMC12347381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.