Evidence map›Paper›PMID 40806945›Full record

ArticleJournal of clinical medicine2025

Efficacy and Safety of a Balanced Gelatine Solution for Fluid Resuscitation in Sepsis: A Prospective, Randomised, Controlled, Double-Blind Trial-GENIUS Trial.

Gernot Marx, Jan Benes, Ricard Ferrer, Dietmar Fries, Johannes Ehler, Rolf Dembinski, Peter Rosenberger, Kai Zacharowski, Manuel Sanchez, Karim Asehnoune and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gernot MarxDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.ORCID 0000-0003-0866-4234
Jan BenesFaculty of Medicine in Hradec Kralove, Charles University in Prague, University Hospital Hradec Kralove, Department of Anaesthesiology, Perioperative Medicine and Intensive Care, Masaryk Hospital, J.E. Purkinje University, 400 96 Usti nad Labem, Czech Republic.
Ricard FerrerServicio de Medicina Intensiva, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron, 119-129, 08035 Barcelona, Spain.ORCID 0000-0002-4859-4747
Dietmar FriesDepartment of Anaesthesia and Critical Care Medicine, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID 0000-0002-1225-4214
Johannes EhlerDepartment of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.
Rolf DembinskiDepartment of Critical Care and Emergency Medicine, Klinikum Bremen-Mitte, St. Jürgen-Straße 1, 28177 Bremen, Germany.
Peter RosenbergerDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Tübingen, Hoppe-Seyler-Straße 3, 72076 Tübingen, Germany.
Kai ZacharowskiDepartment of Anaesthesiology, Intensive Care Medicine & Pain Therapy, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Manuel SanchezHospital Universitario La Paz, Instituto de investigación IdiPAZ, Servicio de Medicina Intensiva, Paseo de la Castellana, 261, 28046 Madrid, Spain.ORCID 0000-0002-8876-3322
Karim AsehnouneService d'Anesthésie Réanimation, Nantes Université, Centre Hospitalier Universitaire de Nantes, Pôle Anaesthésie Réanimations, Service d'Anesthésie Réanimation, Chirurgicale 1, Place Alexis Ricordeau, 44093 Nantes, France.
Bernd Bachmann-MennengaInstitute for Anaesthesiology, Intensive Care and Emergency Medicine, Johannes Wesling Hospital Minden, Hans-Nolte-Str. 1, 32429 Minden, Germany.
Carole IchaiService de Réanimation Polyvalente, IRCAN, Inserm U1081, CNRS UMR7284 et CHU de Nice, Hôpital Pasteur 2, 30 Voie Romaine, CHU de Nice, 06000 Nice, France.
Tim-Philipp SimonDepartment of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.

Funding

B. Braun Melsungen AG, Carl-Braun Str. 1, D-34212 Melsungen industrial funding
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

crystalloidfluid balancefluid resuscitationgelatinesepsis

Identifiers

PMID40806945
PMCPMC12346933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.