Evidence map›Paper›PMID 40806743›Full record

ArticleInternational journal of molecular sciences2025

Genetic Complexity in Spondyloarthritis: Contributions of HLA-B Alleles Beyond HLA-B*27 in Romanian Patients.

Ruxandra-Elena Nagit, Mariana Pavel-Tanasa, Corina Cianga, Elena Rezus, Petru Cianga

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruxandra-Elena NagitImmunology Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0009-0004-9750-1203
Mariana Pavel-TanasaImmunology Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-2802-5993
Corina CiangaImmunology Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Elena RezusRheumatology Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-8175-2583
Petru CiangaImmunology Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-5403-2265

Funding

Romanian Operational Program for Competitiveness 2014-2020, Axis 1, under POC/448/1/1 Re-search Infrastructure Projects for Public R&D Institutions/Universities "Multidisciplinary Medical Research-Development Platform in the NE region (CENEMED)" mySMIS code: 127606.
6 · The paper itself

Abstract

This study examined the distribution and disease associations of non-HLA-B*27 HLA-B alleles in Romanian spondyloarthritis (SpA) patients, aiming to address the underrepresentation of Eastern European populations in immunogenetic research. Methods: We analyzed 263 HLA-B*27-negative patients from Northeastern Romania fulfilling ASAS criteria. HLA-B genotyping was performed at two-digit resolution, and allele distributions were compared with two Romanian HLA-B*27-negative control groups (

Indexed as

Genetic Predisposition to DiseaseHLA-B27 AntigenHLA-B AntigensSpondylarthritisAdultAllelesFemaleGene FrequencyGenotypeHumansMaleMiddle AgedRomaniaHLA-B27 AntigenHLA-B Antigenscross-reactivityHLA-B*27-negativeimmunogeneticsRomanian cohortspondyloarthritis

Identifiers

PMID40806743
PMCPMC12347857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.