Evidence map›Paper›PMID 40806718›Full record

ArticleInternational journal of molecular sciences2025

Inhibition of Tyrosinase and Melanogenesis by a White Mulberry Fruit Extract.

Nuttawadee Prasawang, Nareerat Sutjarit, Athisri Sitthipunya, Prasit Suwannalert, Wutarak Monsuwan, Nisamanee Charoenchon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nuttawadee PrasawangDepartment of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Nareerat SutjaritNutrition Unit, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Athisri SitthipunyaDepartment of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Prasit SuwannalertDepartment of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0002-4622-7310
Wutarak MonsuwanNutrition Unit, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Nisamanee CharoenchonDepartment of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0001-7043-1218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultraviolet B (UVB) radiation is a key factor in the overproduction of melanin in the skin. Melanocytes produce melanin through melanogenesis to protect the skin from UVB radiation-induced damage. However, excessive melanogenesis can lead to hyperpigmentation and increase the risk of malignant melanoma. Tyrosinase is the rate-limiting enzyme in melanogenesis; it catalyzes the oxidation of tyrosine to 3,4-dihydroxy-L-phenylalanine and subsequently to dopaquinone. Thus, inhibiting tyrosinase is a promising strategy for preventing melanogenesis and skin hyperpigmentation. White mulberry (

Indexed as

Enzyme InhibitorsFruitMelaninsMonophenol MonooxygenaseMorusPlant ExtractsAnimalsAntioxidantsCell Line, TumorMelanocytesMelanogenesisMelanoma, ExperimentalMiceUltraviolet RaysZebrafishAntioxidantsEnzyme InhibitorsMelaninsMonophenol MonooxygenasePlant ExtractsB16F10 cellsmelanogenesismulberry crude extracttyrosinase inhibitionUVB radiationzebrafish embryo

Identifiers

PMID40806718
PMCPMC12346983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.