Evidence map›Paper›PMID 40806632›Full record

ArticleInternational journal of molecular sciences2025

Protective Efficacy of

Juyeong Moon, Jin-Ho Lee, Eunwoo Jeong, Harang Park, Hye-Yeong Song, Jinsu Choi, Min-Ah Kim, Kwon-Il Han, Doyong Kim, Han Sung Kim and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Heat-TreatedCells · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juyeong MoonDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0009-0001-3400-4611
Jin-Ho LeeDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Eunwoo JeongDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0009-0002-8144-6989
Harang ParkDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Hye-Yeong SongDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Jinsu ChoiDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0009-0003-6575-6765
Min-Ah KimDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0000-0001-8113-2301
Kwon-Il HanResearch & Development Center, bereum Co. Ltd., Wonju 26362, Republic of Korea.ORCID 0009-0003-5352-2822
Doyong KimDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0000-0002-3302-3263
Han Sung KimDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea.
Tack-Joong KimDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0000-0002-1697-3232

Funding

the Start-up Growth Technology Development Program, funded by the Min-istry of Small and Medium-sized Enterprises RS-2023-00264947
6 · The paper itself

Abstract

Sarcopenia is characterized by a reduction in muscle function and skeletal muscle mass relative to that of healthy individuals. In older adults and those who are less resistant to sarcopenia, glucocorticoid secretion or accumulation during treatment exacerbates muscle protein degradation, potentially causing sarcopenia. This study assessed the preventive effects and mechanisms of heat-killed

Indexed as

DexamethasoneLactiplantibacillus plantarumProbioticsSarcopeniaAnimalsCell LineDisease Models, AnimalForkhead Box Protein O3MaleMiceMuscle Fibers, SkeletalMuscle ProteinsMuscle, SkeletalRatsRats, Sprague-DawleySKP Cullin F-Box Protein LigasesDexamethasoneForkhead Box Protein O3Muscle ProteinsSKP Cullin F-Box Protein LigasesTrim63 protein, ratTripartite Motif ProteinsUbiquitin-Protein LigasesbeLP-KdexamethasoneFoxO3αLactobacillus plantarumMAFbx/atrogin-1MuRF1postbioticsarcopenia

Identifiers

PMID40806632
PMCPMC12348042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.