Evidence map›Paper›PMID 40806532›Full record

ArticleInternational journal of molecular sciences2025

S100A14 as a Potential Biomarker of the Colorectal Serrated Neoplasia Pathway.

Pierre Adam, Catherine Salée, Florence Quesada Calvo, Arnaud Lavergne, Angela-Maria Merli, Charlotte Massot, Noëlla Blétard, Joan Somja, Dominique Baiwir, Gabriel Mazzucchelli and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pierre AdamLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID 0009-0006-3569-4235
Catherine SaléeLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Florence Quesada CalvoLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Arnaud LavergneGIGA Bioinformatics, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Angela-Maria MerliLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Charlotte MassotLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Noëlla BlétardPathological Anatomy and Cytology, University Hospital of Liège (CHU), 4000 Liège, Belgium.
Joan SomjaPathological Anatomy and Cytology, University Hospital of Liège (CHU), 4000 Liège, Belgium.ORCID 0000-0002-7751-7601
Dominique BaiwirGIGA Proteomics, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-1622-0118
Gabriel MazzucchelliLaboratory of Mass Spectrometry, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-8757-8133
Carla Coimbra MarquesAbdominal Surgery Department, University Hospital of Liège (CHU), 4000 Liège, Belgium.
Philippe DelvennePathological Anatomy and Cytology, University Hospital of Liège (CHU), 4000 Liège, Belgium.
Edouard LouisLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.
Marie-Alice MeuwisLaboratory of Translational Gastroenterology, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-8923-2670

Funding

AbbVieCelltrionCHU of Liège grantsDr. Falk PharmaFonds Léon FredericqFresenius KabiFund for Scientific Research FC 44203HOMISTASIS PROJECTJanssen PharmaceuticalsUniversity of Liège
6 · The paper itself

Abstract

Accounting for 15-30% of colorectal cancer cases, the serrated pathway remains poorly characterized compared to the adenoma-carcinoma sequence. It involves sessile serrated lesions as precursors and is characterized by BRAF mutations (BRAF

Indexed as

AdenomaBiomarkers, TumorColorectal NeoplasmsAgedFemaleGene Expression Regulation, NeoplasticHumansMaleMicrosatellite InstabilityMiddle AgedMutationProto-Oncogene Proteins B-rafBiomarkers, TumorBRAF protein, humanProto-Oncogene Proteins B-rafbiomarkerproteomicsS100A14serrated pathwaysessile serrated lesions

Identifiers

PMID40806532
PMCPMC12347601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.