Evidence map›Paper›PMID 40806470›Full record

ArticleInternational journal of molecular sciences2025

Influence of a Th17-Inducing Cytokine Milieu on Phenotypical and Functional Properties of Regulatory T Cells in Chronic Inflammatory Arthritis.

Tobias Schwarz, Giovanni Almanzar, Marie Wulfheide, Robert Woidich, Marie-Therese Holzer, Timotheos Christoforou, Leonie Karle, David Radtke, Franziska Brauneiser, Thomas Haaf and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Tobias SchwarzDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0009-0009-3004-4067
Giovanni AlmanzarDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Marie WulfheideDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Robert WoidichDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Marie-Therese HolzerDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0002-2064-6728
Timotheos ChristoforouDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0009-0008-5970-982X
Leonie KarleDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
David RadtkeDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Franziska BrauneiserDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Thomas HaafDepartment of Human Genetics, University of Wuerzburg, 97074 Wuerzburg, Germany.ORCID 0000-0002-0737-0763
Ramya PotabattulaDepartment of Human Genetics, University of Wuerzburg, 97074 Wuerzburg, Germany.ORCID 0000-0002-2858-8104
Gabriela OrtegaDepartment of Psychiatry, Division of Molecular Psychiatry, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Klaus-Peter LeschDepartment of Psychiatry, Division of Molecular Psychiatry, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Arne SchäferDepartment of Internal Medicine II, Rheumatology/Clinical Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0001-6600-3691
Sandrine BenoitDepartment of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Astrid SchmiederDepartment of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0002-6421-9699
Matthias GoebelerDepartment of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0001-7095-9848
Marc SchmalzingDepartment of Internal Medicine II, Rheumatology/Clinical Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Martin FeuchtenbergerDepartment of Internal Medicine II, Rheumatology/Clinical Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0001-8028-8099
Martina PrelogDepartment of Pediatrics, Pediatric Rheumatology/Special Immunology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.

Funding

Bavarian Innovation Fund none availableNovartis Pharma none available
6 · The paper itself

Abstract

Considering the high plasticity of FoxP3

Indexed as

ArthritisTh17 CellsT-Lymphocytes, RegulatoryAdultAgedCross-Sectional StudiesCytokinesDNA MethylationFemaleForkhead Transcription FactorsHumansMaleMiddle AgedYoung AdultCytokinesForkhead Transcription FactorsFOXP3 protein, humanFoxP3methylationpsoriatic arthritisRegulatory T cellsTh17 cellsTSDR

Identifiers

PMID40806470
PMCPMC12347858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.